ID N4VI75_COLOR Unreviewed; 1535 AA.
AC N4VI75;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Dicer-like protein 1 {ECO:0000256|ARBA:ARBA00020797};
GN Name=DCL1 {ECO:0000313|EMBL:TDZ22893.1};
GN ORFNames=Cob_v004242 {ECO:0000313|EMBL:TDZ22893.1};
OS Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS
OS 414 / MAFF 240422) (Cucumber anthracnose fungus) (Colletotrichum
OS lagenarium).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum orbiculare species complex.
OX NCBI_TaxID=1213857 {ECO:0000313|EMBL:TDZ22893.1, ECO:0000313|Proteomes:UP000014480};
RN [1] {ECO:0000313|Proteomes:UP000014480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=23252678; DOI=10.1111/nph.12085;
RA Gan P., Ikeda K., Irieda H., Narusaka M., O'Connell R.J., Narusaka Y.,
RA Takano Y., Kubo Y., Shirasu K.;
RT "Comparative genomic and transcriptomic analyses reveal the hemibiotrophic
RT stage shift of Colletotrichum fungi.";
RL New Phytol. 197:1236-1249(2013).
RN [2] {ECO:0000313|Proteomes:UP000014480}
RP GENOME REANNOTATION.
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=30893003; DOI=10.1094/MPMI-12-18-0352-A;
RA Gan P., Tsushima A., Narusaka M., Narusaka Y., Takano Y., Kubo Y.,
RA Shirasu K.;
RT "Genome sequence resources for four phytopathogenic fungi from the
RT Colletotrichum orbiculare species complex.";
RL Mol. Plant Microbe Interact. 32:1088-1090(2019).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the helicase family. Dicer subfamily.
CC {ECO:0000256|PROSITE-ProRule:PRU00657}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDZ22893.1}.
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DR EMBL; AMCV02000009; TDZ22893.1; -; Genomic_DNA.
DR STRING; 1213857.N4VI75; -.
DR EnsemblFungi; ENH80776; ENH80776; Cob_10441.
DR eggNOG; KOG0701; Eukaryota.
DR HOGENOM; CLU_000907_4_3_1; -.
DR OrthoDB; 342391at2759; -.
DR Proteomes; UP000014480; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18034; DEXHc_dicer; 1.
DR CDD; cd00593; RIBOc; 2.
DR Gene3D; 3.30.160.380; Dicer dimerisation domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 2.
DR InterPro; IPR038248; Dicer_dimer_sf.
DR InterPro; IPR005034; Dicer_dimerisation_dom.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR14950:SF62; DICER-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR14950; DICER-RELATED; 1.
DR Pfam; PF03368; Dicer_dimer; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF00636; Ribonuclease_3; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00535; RIBOc; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF69065; RNase III domain-like; 2.
DR PROSITE; PS51327; DICER_DSRBF; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS00517; RNASE_3_1; 1.
DR PROSITE; PS50142; RNASE_3_2; 2.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Antiviral protein {ECO:0000256|ARBA:ARBA00022721};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000014480};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00657}.
SQ SEQUENCE 1535 AA; 174613 MW; F6BF6486739A649E CRC64;
MSYPGSSVVE TKKPLKLSTE QLVVSFRDDA EELAEHQDVY QDEDENGGED DYRRFSQNPE
RPRTISQRKR ADQAVLQDFI RKEGAKLKDS KPEVLEDMSA TGLFKKDKII HTPREYQLEL
FERAKKRNVI AVLDTGSGKT LIAALLLRHV LEQEMIDRAA GKPKRIAFFL VDKVSLVFQQ
HAVLDCNLSH DIAKFCGEMV DAMWSNEFWE KEFDKNQVIV CTAAILQKCL TQSYIRMDQI
NLLIFDEAHH TKKGHPYARI IKDFYIKEDK SKRPKVFGMT ASPVDAQTDV KIAAARLESL
LDSEIATISE ESSSLTPHRH KPVEVEVHYE TLPIPTATQL YSKVLALVRH NTHFGKELSY
SFQATSFLGP WLADRFWQLF LTDDTILRLS HKTDMTDYGL DVTGRETSAV QQLPNVLKSH
NFCPVEPSLN HLSVKVLRLW EELRTRFSKP NDRKCIVFVE MRLTALLLND LFQQDGTKLP
YLNSAVLVGN RPDPGATNMS FRGQILNITK FRQGSVNCLF ATQVAEEGLD IPDCNLVIRF
DLYKSAIQYI QSKGRARQRN SEYLSFVEGG NGKHARTIAQ ASYDQTELRR FCAALPEDRK
IASLDLNSSV LQGEAHFRSY VIESTGAKLT WMSSLDVLAR FTASLRQSND EILVPDYVVI
NQGQNFVAEV QLPSKSPILS KTGFPHRNKQ SARCSAAFEM CKELIKKKYI DHYLNPVFVK
KLPAMRNARL AVSSNKSAQY KMRTQPEIWT RLGDFDRLFV TVLKLATPEA IGRTSKPLLL
LTREQLPDLP DIPLFFGNEQ HSKVLPVSLP VPIAVSAEEA RILKEFTFRV FKDVFSKEYE
APVSDTPYFF APTKHGHSVV LSDIDCPASL VDWEHLHSTA GKEYMSWDNE TPDEFFKDKL
VTDPYAGSRK LYLRGVRKDM KPLDPVPEGV PDPGHRAWGD ARVEKNIKEY SVSLWMKSRL
ERSSKWRVDQ PVVEAEVVSL RRNLLDDFIE QTEEISRICY VILEPMRVST LPIETTIMAF
AFPAIIHRIN SVMIALDACD YLQLEIRPDL ALEAMTKDSD NSDEHDQEKI NFQGGMGNNY
ERLEFLGDCF LKMATTIAIF TSRPDDDEFQ YHVQRMLLIC NQNLFNKAVD RKLQEYVRSQ
SFDRRSWYPQ GLKLVRGKAG QPIDQHALAD KSIADVCEAL IGAAYLTYAD SGNYDMAIRA
VTVMVREKTH RMTSWKDYYA AYSAPPWQFR DETVMQREDA RRIKEKLGYE FKSPALLRSA
FKHPSYPRAY ENLPNYQRLE FLGDALLDMV CVDFLFKRFP NADPQWLTEH KMAMVSNQFL
ASLCVKLGLH KHILVGSSSM MSATEEFVSS LNLAQSEAEA EAGETGIFSQ DYWTNVKSSP
KYLSDVVEAY VGAVFVDSGY DYSQVCAFFD KHIRPFFTDM ALYDSFANRH PVTKLSHLLY
NTYGCQEWRL TTISAVPPAS EGAQAVTSNK LATAVIIHGR PWASVIGEST KYSKIASAKV
AIEELEGMSV EGFKREHGCD CKVEGEDTMD HGTAI
//
