ID N4VU57_COLOR Unreviewed; 1151 AA.
AC N4VU57;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=DNA repair protein REV1 {ECO:0000256|ARBA:ARBA00020399, ECO:0000256|PIRNR:PIRNR036573};
DE EC=2.7.7.- {ECO:0000256|PIRNR:PIRNR036573};
GN Name=rev1 {ECO:0000313|EMBL:TDZ17790.1};
GN ORFNames=Cob_v009307 {ECO:0000313|EMBL:TDZ17790.1};
OS Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS
OS 414 / MAFF 240422) (Cucumber anthracnose fungus) (Colletotrichum
OS lagenarium).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum orbiculare species complex.
OX NCBI_TaxID=1213857 {ECO:0000313|EMBL:TDZ17790.1, ECO:0000313|Proteomes:UP000014480};
RN [1] {ECO:0000313|Proteomes:UP000014480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=23252678; DOI=10.1111/nph.12085;
RA Gan P., Ikeda K., Irieda H., Narusaka M., O'Connell R.J., Narusaka Y.,
RA Takano Y., Kubo Y., Shirasu K.;
RT "Comparative genomic and transcriptomic analyses reveal the hemibiotrophic
RT stage shift of Colletotrichum fungi.";
RL New Phytol. 197:1236-1249(2013).
RN [2] {ECO:0000313|Proteomes:UP000014480}
RP GENOME REANNOTATION.
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=30893003; DOI=10.1094/MPMI-12-18-0352-A;
RA Gan P., Tsushima A., Narusaka M., Narusaka Y., Takano Y., Kubo Y.,
RA Shirasu K.;
RT "Genome sequence resources for four phytopathogenic fungi from the
RT Colletotrichum orbiculare species complex.";
RL Mol. Plant Microbe Interact. 32:1088-1090(2019).
CC -!- FUNCTION: Deoxycytidyl transferase involved in DNA repair. Transfers a
CC dCMP residue from dCTP to the 3'-end of a DNA primer in a template-
CC dependent reaction. May assist in the first step in the bypass of
CC abasic lesions by the insertion of a nucleotide opposite the lesion.
CC Required for normal induction of mutations by physical and chemical
CC agents. {ECO:0000256|PIRNR:PIRNR036573}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036573}.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945, ECO:0000256|PIRNR:PIRNR036573}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDZ17790.1}.
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DR EMBL; AMCV02000027; TDZ17790.1; -; Genomic_DNA.
DR AlphaFoldDB; N4VU57; -.
DR STRING; 1213857.N4VU57; -.
DR EnsemblFungi; ENH87467; ENH87467; Cob_04288.
DR eggNOG; KOG2093; Eukaryota.
DR HOGENOM; CLU_003901_1_1_1; -.
DR OrthoDB; 169741at2759; -.
DR Proteomes; UP000014480; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0070987; P:error-free translesion synthesis; IEA:UniProt.
DR GO; GO:0042276; P:error-prone translesion synthesis; IEA:InterPro.
DR CDD; cd17719; BRCT_Rev1; 1.
DR CDD; cd01701; PolY_Rev1; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1490; -; 1.
DR Gene3D; 6.10.250.1630; -; 3.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR Gene3D; 1.20.58.1280; DNA repair protein Rev1, C-terminal domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR025527; HUWE1/Rev1_UBM.
DR InterPro; IPR012112; REV1.
DR InterPro; IPR031991; Rev1_C.
DR InterPro; IPR038401; Rev1_C_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45990; DNA REPAIR PROTEIN REV1; 1.
DR PANTHER; PTHR45990:SF1; DNA REPAIR PROTEIN REV1; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF16727; REV1_C; 1.
DR Pfam; PF14377; UBM; 3.
DR PIRSF; PIRSF036573; REV1; 2.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|PIRNR:PIRNR036573};
KW DNA repair {ECO:0000256|PIRNR:PIRNR036573};
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634,
KW ECO:0000256|PIRNR:PIRNR036573};
KW DNA-binding {ECO:0000256|PIRNR:PIRNR036573};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Nucleotidyltransferase {ECO:0000256|PIRNR:PIRNR036573};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR036573};
KW Reference proteome {ECO:0000313|Proteomes:UP000014480};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR036573}.
SQ SEQUENCE 1151 AA; 127897 MW; 624536A1CC8DA4B4 CRC64;
MGSRLDKNSS QVRKRIESHQ FDDEAGEEYE GSAFGGFGDY FRRKKIKLQN LDADIRASSS
DKPQIFKGVV AHVMGYTQPP LHVLHRELVQ HGAGFLQYLD SKTMATHIIA SSVPPKKSVD
YSRYRLVKPA WVTESIQAGK LLPWSDFRVD NDGPRQKVLK FDSSNKLSQA TPQQKQGYRE
QTENSFYTGQ FRASTNSPAT PSLGRFVERA ESPLARKHGR GSNGPTPLSP FKVTRAGPKG
GPDEFDDVEI DELMVDILPA ESPEKTDEKD EKPAVSEIEP ETQAPTDKEV KREASLPENM
TSEEHNAWLL SDPKIWKSST ANPDFLKQFY SESRLHHLST WKAELKSRVQ RLAKEKGPAM
APAKRKTGSR RYVMHVDFDS FFCAVSLKRH PELVDKPTVV AHSSGPGSEI ASCNYVARKF
GVKNGMWMKR ALDLCPDIKV LPYDFPAYEE ASRHFYEAIL DLGGIVQSVS IDEAFVDITS
LVLSSAGSDG AGVEEGSIWR EQEKADQMAA ELRDKIKAST GCAVSVGLGG NILLAKVALR
RAKPAGQFQM KPEQVLEVIG ELEVKDLPGV AYSLSGKLEE IGVKYVKDIR QVSKERLSSS
LGPKTGERLW EYARGIDRTE VGEQPPRKSV SAEVNWGIRF INQQESEDFV MNLCKELERR
LLNEQVRGKQ LTTKIMRRAQ DTPLDPAKHL GHGKCDSFSK SIVFGVATHD AEIIGKEAVS
ILRSYRFTPG DLRGLGVQLT RLEPIKSGPS GPENSQRKLA FPTFNGSISA KKAQADPIEE
SRSPSKPKSN SRGATEDPIA DDPLTPRKPK VHPALALARA GEKDDKAHTP LNIMGTQFIL
PSQVDPAVLA ELPSDIRAKL LKGRSAPAPR QQASPQAKSR SNSPAVQEEV PSQVDPEVFN
ALPDDMKAEV LAQYGRRTNQ TRLPQSPRKD RLIQPKKPIT PTKRGRSLFN NARERQHDAV
ANRMQTSFLP NKGPLPAFRE SEELDPEFLA ELPEDVRREV IEDHRRKRLN QRSGLNFNAP
RRHHAAETEA LPGGQTKLQF PAPPPKATFM GSAVKSAQEI KDMIEAWHDG TRATGPHEDD
VVMFKKYLGK VVLEERDMPK AAKLVQWLEW LVEDDGSEGR GGKQGWRATL SGIKAEVQKA
VEQRGLGPLK L
//
