ID N4XCA8_COCH4 Unreviewed; 525 AA.
AC N4XCA8;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=glucan 1,4-alpha-glucosidase {ECO:0000256|ARBA:ARBA00012593};
DE EC=3.2.1.3 {ECO:0000256|ARBA:ARBA00012593};
DE AltName: Full=1,4-alpha-D-glucan glucohydrolase {ECO:0000256|ARBA:ARBA00033473};
DE AltName: Full=Glucan 1,4-alpha-glucosidase {ECO:0000256|ARBA:ARBA00033442};
GN ORFNames=COCC4DRAFT_183527 {ECO:0000313|EMBL:ENI10629.1};
OS Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T) (Southern
OS corn leaf blight fungus) (Bipolaris maydis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=665024 {ECO:0000313|EMBL:ENI10629.1, ECO:0000313|Proteomes:UP000012338};
RN [1] {ECO:0000313|EMBL:ENI10629.1, ECO:0000313|Proteomes:UP000012338}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C4 / ATCC 48331 / race T {ECO:0000313|Proteomes:UP000012338};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000012338}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C4 / ATCC 48331 / race T {ECO:0000313|Proteomes:UP000012338};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues
CC successively from non-reducing ends of the chains with release of
CC beta-D-glucose.; EC=3.2.1.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001863};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 15 family.
CC {ECO:0000256|ARBA:ARBA00006188}.
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DR EMBL; KB733444; ENI10629.1; -; Genomic_DNA.
DR RefSeq; XP_014084538.1; XM_014229063.1.
DR AlphaFoldDB; N4XCA8; -.
DR GeneID; 25840866; -.
DR HOGENOM; CLU_012173_2_0_1; -.
DR OrthoDB; 1586242at2759; -.
DR Proteomes; UP000012338; Unassembled WGS sequence.
DR GO; GO:0004339; F:glucan 1,4-alpha-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005976; P:polysaccharide metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011613; GH15-like.
DR InterPro; IPR000165; Glucoamylase.
DR InterPro; IPR046966; Glucoamylase_active_site.
DR PANTHER; PTHR31616:SF11; GLUCOAMYLASE, INTRACELLULAR SPORULATION-SPECIFIC; 1.
DR PANTHER; PTHR31616; TREHALASE; 1.
DR Pfam; PF00723; Glyco_hydro_15; 1.
DR PRINTS; PR00736; GLHYDRLASE15.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS00820; GLUCOAMYLASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ENI10629.1}.
FT DOMAIN 55..517
FT /note="GH15-like"
FT /evidence="ECO:0000259|Pfam:PF00723"
FT REGION 357..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 57947 MW; 19E99A63B3EE8B5D CRC64;
MLPRVFLLTG FVHHAYTLSI PRLPSLATFA ASSRVQQQQP LQDTLDAWIK HEERIALDKL
LANIAPGGSN VQGKGVAEGT VIASPSQDGP DYWFQWVRDA AITMDTLVNI YADDPSSSRA
SSLSTILDAY TSLQGDIQRT SNPSGTFDDL SGLGEPKFQV DGKPFTGSWG RPQRDGPALR
ALTLMHYLRE YNASHPSLWS SPNSEDFFGS FYTAEMPPRS IIKADLEYVS HFWNQSGFDL
WEEVEGLHFF TLMVSARSLR EGSHLARVFG DVGAADWYQK QAGYIENLLG KFWNAQKGHL
VETLWSKRSG LDCGLLLGSL HALPKSGSED DDVVYPPWSD EILVSLLALT RDQRDRFPIN
SNPSGQDDDD DDVDESTFQG TGLGRYPEDV YDGYGNSNRG GNPWFLCTSS AAEILYRTAS
HISATGNLTL TDVGLPFYES LLGSSSLDVD VGTFGPTDAL FHSVIERLQS TGDEFLQVVK
THVDAEGSMS EQFDRVTGYM RGAQHLTWSY GAFLQAARAR KISVH
//
