ID N6UUV7_DENPD Unreviewed; 397 AA.
AC N6UUV7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0000259|Pfam:PF07885};
DE Flags: Fragment;
GN ORFNames=YQE_01028 {ECO:0000313|EMBL:ENN82602.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ENN82602.1};
RN [1] {ECO:0000313|EMBL:ENN82602.1, ECO:0000313|Proteomes:UP000019118}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
RN [2] {ECO:0000313|EnsemblMetazoa:ENN82602}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR EMBL; APGK01011346; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; APGK01011347; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; APGK01011348; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; APGK01011349; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; APGK01011350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; APGK01011351; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB738451; ENN82602.1; -; Genomic_DNA.
DR AlphaFoldDB; N6UUV7; -.
DR EnsemblMetazoa; ENN82602; ENN82602; YQE_01028.
DR HOGENOM; CLU_046907_0_0_1; -.
DR OMA; KMVHVPD; -.
DR Proteomes; UP000019118; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR PANTHER; PTHR11003:SF333; TWIK FAMILY OF POTASSIUM CHANNELS PROTEIN 7; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 137..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..189
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 226..297
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ENN82602.1"
SQ SEQUENCE 397 AA; 45061 MW; 8A6F9239198EF86B CRC64;
MQEREDRPTT TPLIAVETRV QIGSSMDFKS RVRDWWQSLR LKAFWQHDGL LVALAGYTVL
GGLVFRRLEY PAELSRIEYH NSTLSQTRQN LIRIIVNNSD LRNLISIELD NYEKALEASF
NDGIPLRPKV EMAKWTTLKA VFFCSTVLTT IGYGNIVPMT LEGKAFCVVF ALVGIPLTMT
VIADWGRLFA STLSAVMQQI PPLPKSLRNA MVARRTSSYA LSAVCFLFVY LAAGAAIFVL
WEEEWSFFDG FYFCFITMTT IGFGDLVPTQ PKYMLLCTLY ILVGLALTST IIELVRRQYA
QSWRQLQALR GPLAENFWKF ADNAPGLDVL AFQQDLMKVL TVVSMPKRIG SRKDKKNKGK
VDKDWEDALQ VVIQDITKKC SNKEQQLVQI VVYESSV
//
