ID N6W9K5_9ACTO Unreviewed; 291 AA.
AC N6W9K5;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase {ECO:0000313|EMBL:ENO19250.1};
DE EC=4.2.1.107 {ECO:0000313|EMBL:ENO19250.1};
GN ORFNames=HMPREF9004_0169 {ECO:0000313|EMBL:ENO19250.1};
OS Schaalia cardiffensis F0333.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Schaalia.
OX NCBI_TaxID=888050 {ECO:0000313|EMBL:ENO19250.1, ECO:0000313|Proteomes:UP000013015};
RN [1] {ECO:0000313|EMBL:ENO19250.1, ECO:0000313|Proteomes:UP000013015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0333 {ECO:0000313|EMBL:ENO19250.1,
RC ECO:0000313|Proteomes:UP000013015};
RA Aqrawi P., Ayvaz T., Bess C., Blankenburg K., Coyle M., Deng J., Forbes L.,
RA Fowler G., Francisco L., Fu Q., Gibbs R., Gross S., Gubbala S., Hale W.,
RA Hemphill L., Highlander S., Hirani K., Jackson L., Jakkamsetti A.,
RA Javaid M., Jayaseelan J.C., Jiang H., Joshi V., Korchina V., Kovar C.,
RA Lara F., Lee S., Liu Y., Mata R., Mathew T., Munidasa M., Muzny D.,
RA Nazareth L., Ngo R., Nguyen L., Nguyen N., Okwuonu G., Ongeri F.,
RA Palculict T., Patil S., Petrosino J., Pham C., Pham P., Pu L.-L., Qin X.,
RA Qu J., Reid J., Ross M., Ruth R., Saada N., San Lucas F., Santibanez J.,
RA Shang Y., Simmons D., Song X.-Z., Tang L.-Y., Thornton R., Warren J.,
RA Weissenberger G., Wilczek-Boney K., Worley K., Youmans B., Zhang J.,
RA Zhang L., Zhao Z., Zhou C., Zhu D., Zhu Y.;
RT "Reference genome for the Human Microbiome Project.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENO19250.1}.
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DR EMBL; AQHZ01000001; ENO19250.1; -; Genomic_DNA.
DR RefSeq; WP_005961747.1; NZ_KB822674.1.
DR AlphaFoldDB; N6W9K5; -.
DR STRING; 888050.HMPREF9004_0169; -.
DR PATRIC; fig|888050.3.peg.168; -.
DR eggNOG; COG2030; Bacteria.
DR HOGENOM; CLU_040078_1_0_11; -.
DR OrthoDB; 5522043at2; -.
DR Proteomes; UP000013015; Unassembled WGS sequence.
DR GO; GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR002539; MaoC-like_dom.
DR PANTHER; PTHR13078:SF56; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2; 1.
DR PANTHER; PTHR13078; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:ENO19250.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013015}.
FT DOMAIN 164..262
FT /note="MaoC-like"
FT /evidence="ECO:0000259|Pfam:PF01575"
SQ SEQUENCE 291 AA; 32893 MW; 62B6B5C21A49DF51 CRC64;
MAINTEMVGK TFGPFVRDYT FRDLELFALG CGAGIDGKDG LEYINEHDER DPHLKVLPMF
GAMLIVDSEV TRTIDYGYNY AGSLHWGFDI TFHKPITKMS DHLETMVRLE GLYDRGEGRG
LLAQHIGDTY DSDGNLLFTN ESWDCLIYDG GWGGPKPPKD IVEMPDRPAD VEITETIPEN
QALIYRLSGD YHPQHIDWDY AAENGEPRPI LHAISYAGVV MRHAINAFVP GEPERITRFK
TRITSPVHPG TTLKTRLWKI KEGELRFALV DADADETGAK PHLNWGIIEY R
//
