ID N6XT60_9RHOO Unreviewed; 901 AA.
AC N6XT60;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=B447_04098 {ECO:0000313|EMBL:ENO82515.1};
OS Thauera sp. 27.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Thauera.
OX NCBI_TaxID=305700 {ECO:0000313|EMBL:ENO82515.1, ECO:0000313|Proteomes:UP000013140};
RN [1] {ECO:0000313|EMBL:ENO82515.1, ECO:0000313|Proteomes:UP000013140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=27 {ECO:0000313|EMBL:ENO82515.1,
RC ECO:0000313|Proteomes:UP000013140};
RA Liu B., Shapleigh J.P., Frostegard A.H.;
RT "Draft Genome Sequences of 6 Strains from Genus Thauera.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENO82515.1}.
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DR EMBL; AMXB01000005; ENO82515.1; -; Genomic_DNA.
DR RefSeq; WP_002926692.1; NZ_AMXB01000005.1.
DR AlphaFoldDB; N6XT60; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG3452; Bacteria.
DR eggNOG; COG3829; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR Proteomes; UP000013140; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ENO82515.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000013140};
KW Transferase {ECO:0000313|EMBL:ENO82515.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 284..354
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 404..476
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 480..532
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 533..571
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 676..892
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 901 AA; 100180 MW; 379E0902E9AFF5A2 CRC64;
MHAPPSDPAP PRWYWAVPYV VVTLFAVSML ALVWLLQQRE SDVERGALAR DLQWTEQAIR
RVVLGTEEFL GQLARDMAAG TLEHDGFQQR ANEHLAVNPA LTNIAWVGRD QAVRWTAPFD
ALDWLAGDTL LGPQVQGFQH SALSSRLTYG AAYRNARGDA VLEVFVPVHR QGEFFGALVA
AYSVERMISR LVPDWFTEKY RLAVLDTDGV ALALSSALPD REHHLALELV LEPPRNGMRL
QAMAFRPGGD VMHALPAVII VGLSLLVLWG LWMLRGHMQR RVQVERERDR LFNLSLDLLC
IVDLEGRFRR CNPAFERVLG HDPATLPGAL MIDFVHAEDV ASTLDNMRRL AGGEPVSFEN
RCRCADGSYK WLAWSVNPVR GEGLVYAVAH DVTGRKAAED ALRAESAFRK AMEDSVVTGL
RAIDLSGRII YVNSAFCRMV GFAESELVGT VAPFPYWPPE QLAICERNLA MTLSGQAPRS
GFEMRIQRKN GERFDARFYL SPLIDLTGRQ TGWMASITDI TEPKRVRAAL EAAHERFEAV
LDGLDAAVFV ADARTDEILF ANLAFKRIHG FDAVGRTVRG VAVPQPERGD YRVDPRNLAP
ADLPRELFDG ELQHPLSGRW YHVREQATRW VDGRVVRMGI ATDITDRKQT AEVARQQEER
LQRTSRLITM GEMASTLAHE LNQPLSAIAN YCAGSVTRLQ AGNAKQEDIL AAMQKASFQA
ERAGKIIRRV REFVKKSEPR RAAVSIVDIL EDAIGFADID ARRTGIRIVT AVEPGLPAVY
ADRIMIEQVL LNLVRNGIDA MADALPERRV LTVRVRGCGP GQVEVAVIDQ GHGISEEGRS
RLFTPFYTTK AEGMGMGLNI CRSIVEFHDG RLIVDDNPEG GTIFSFILPT EIASERVARS
A
//
