ID N9Q4K7_9GAMM Unreviewed; 950 AA.
AC N9Q4K7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Monovalent cation/H+ antiporter subunit A {ECO:0008006|Google:ProtNLM};
GN ORFNames=F888_00151 {ECO:0000313|EMBL:ENX40679.1};
OS Acinetobacter courvalinii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=280147 {ECO:0000313|EMBL:ENX40679.1, ECO:0000313|Proteomes:UP000013200};
RN [1] {ECO:0000313|EMBL:ENX40679.1, ECO:0000313|Proteomes:UP000013200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIPH 3623 {ECO:0000313|EMBL:ENX40679.1,
RC ECO:0000313|Proteomes:UP000013200};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cerqueira G., Feldgarden M., Courvalin P., Perichon B.,
RA Grillot-Courvalin C., Clermont D., Rocha E., Yoon E.-J., Nemec A.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Acinetobacter sp. NIPH 3623.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENX40679.1}.
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DR EMBL; APSA01000001; ENX40679.1; -; Genomic_DNA.
DR RefSeq; WP_005280854.1; NZ_VZOE01000001.1.
DR AlphaFoldDB; N9Q4K7; -.
DR STRING; 1217698.F888_00151; -.
DR GeneID; 80105636; -.
DR PATRIC; fig|1217698.3.peg.146; -.
DR HOGENOM; CLU_007100_2_0_6; -.
DR Proteomes; UP000013200; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF04039; MnhB; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 609..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 638..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 700..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..775
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 796..817
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 823..844
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 864..884
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 904..930
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 69..105
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 130..414
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 624..685
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 695..778
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
FT DOMAIN 798..924
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 950 AA; 102973 MW; 85218DD82F8AC327 CRC64;
MDTSVLPIII LLPLILGTTL VSQLQRISRG VTALGAIGIS LSCFILLLTQ AETVLQGNTL
QQSWDWLPQL GINLSFRLDA LGLLFGLLIS GIGTLIYIYA YYYLSPKNSL SKLYQLLMLF
MAAMLGISLS NNLILLLVFW ELTSISSFLL VGYWSQYDAA QRGARMALTI TGMGGLAMLG
GFVLLGQITG TYQIDQLVLM KDTIQQHELF VPTLLLILLG AFTKSAQFPF HFWLPNAMAA
PTPVSAYLHS ATMVKAGIFL LARLAPIFIG AALYHNIVTF VGLFTLCMAA GFAIFKEDLK
GLLAYSTISH LGLIVCLLGI GSPLAVAAAV FHIINHATFK AALFMIAGII DHETGTRDLR
KLSGVWQLLP FTATLTMITA ASMAGVPLTN GFISKEMFFT ELLANLSGPV MVISAIIATL
AGIFAVSYSI RLVHGVFFDG PLGKQVPNKD AHEPPLGMRL PAIILATLCI LVGILPALLA
GTLVNSVTRA SLAQPEFEGV HLAIWHGVNA PLLMSVIALI GGTLFYFALA KDGRIRKIDL
DPHLGKFQGR ILFDLFLKHL LLSSRRMKQT TENGSLQSYL LWIVLFSIVM VALPLLNQGL
TTGTRELTHA PWVAIVLWLT LFSGCWMMLW FHHERIKAVL ISGAVGLVVT MVFVTLSAPD
LALTQITVDV VTTVLLLMSL SLLPQLTPYE SSRSRRWRDA TLAIVGGLGI GWITWLLLTR
DHNSISWFFM QQAIPLGGGS NVVNVILVDF RGFDTFGEIT VLGIAAIGAL CLMDGMRAHG
TTMTQGLTYR FNPSPLMLRI TASWILPLAL VVSVYIFMRG HNLPGGGFIA GLITSMALVI
QYIVLGQDQT EQMIKAKSGR LYELWIGSGL TIAGLTGIAA WFWARPFLTS AHIYVEAPLL
GKMHLASAVA FDTGVYITVV GATMLLISVL GDSRHSSMSG PIPSGDKENG
//
