ID N9TWP7_9GAMM Unreviewed; 697 AA.
AC N9TWP7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Peptidase M50 {ECO:0000313|EMBL:ENY70500.1};
GN ORFNames=G114_17991 {ECO:0000313|EMBL:ENY70500.1};
OS Aeromonas diversa CDC 2478-85.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=1268237 {ECO:0000313|EMBL:ENY70500.1, ECO:0000313|Proteomes:UP000023775};
RN [1] {ECO:0000313|EMBL:ENY70500.1, ECO:0000313|Proteomes:UP000023775}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2478-85 {ECO:0000313|EMBL:ENY70500.1,
RC ECO:0000313|Proteomes:UP000023775};
RX PubMed=23792745; DOI=10.1128/genomeA.00330-13;
RA Farfan M., Spataro N., Sanglas A., Albarral V., Loren J.G., Bosch E.,
RA Fuste M.C.;
RT "Draft Genome Sequence of the Aeromonas diversa Type Strain.";
RL Genome Announc. 1:S69-S82(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50B family.
CC {ECO:0000256|ARBA:ARBA00007931}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENY70500.1}.
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DR EMBL; APVG01000071; ENY70500.1; -; Genomic_DNA.
DR RefSeq; WP_005361662.1; NZ_CDCE01000005.1.
DR AlphaFoldDB; N9TWP7; -.
DR PATRIC; fig|1268237.3.peg.3529; -.
DR eggNOG; COG0845; Bacteria.
DR eggNOG; COG1994; Bacteria.
DR OrthoDB; 9759690at2; -.
DR Proteomes; UP000023775; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR001193; MBTPS2.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR008915; Peptidase_M50.
DR PANTHER; PTHR13325:SF3; MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE; 1.
DR PANTHER; PTHR13325; PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 143..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 187..263
FT /note="Peptidase M50"
FT /evidence="ECO:0000259|Pfam:PF02163"
FT DOMAIN 449..487
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
SQ SEQUENCE 697 AA; 78242 MW; D425C57BF62B44F4 CRC64;
MTPLPPLRDD LRLDAAAPGL DGAPQWVLSD AFSGRYYKLT ATALRLLRHW SCGNAEGVLA
AANREVGLPL NEQDLQQLLL FLRGHDLISS RDPMQRAGYP EKATRRRVSF WRHLLHQYLF
FRLPLWRPDP LLTRLWPTLR RLAGLRLLLP WLLLVALFLL GRDWARYHHA FPQLFNLEGA
LLLGASLLLA KFCHELGHAF MAKRAGCRVR SMGVAFVVML PMFYTDVSDA WRVQDRRARL
WIGAGGVLAE MLLASLALLA WLLLPDGMLR SAALLLSSVT WVGSLLINLN PLMRFDGYFL
LSDLWRIDNL QDRAFALCRW HLRELLFGYG SATPEVWSPR MRRRLLLWGY ASWVWRFILF
LGIALTVYHF FFKLLGIALM AVEIGWFIAL PIVRELTLWW QQRQRANARR ALLTAAGLLL
LLGALLIPWR TRIAIPAMLE AGYVGTLYAP VPARVQRVLI ADGDRVEANQ VLISLSSPDL
DARLAIARHR VTALELELRR QSARKETASD GPVLARRLAE ALTEYRGWVA QRERLQLRAL
QAGVVRDLAR DLAPGRWLGV EQPLLRIVDT GVGRVRGYVQ EESLARLTPG ARGEFIADDP
SAAALPVRLD HIDATGIASL PLEALASDRG GPIGVRRDAE QRAVPLQAHY GVTLSPAHPL
PGAGQQRGLV LLDGQAESLL GRFGRRAWAL AIRESGF
//
