ID NUSB_NEIMA Reviewed; 141 AA.
AC Q9JVD5; A1IQT6;
DT 02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=NMA0885;
OS Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 /
OS Z2491).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=122587;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15465 / Z2491;
RX PubMed=10761919; DOI=10.1038/35006655;
RA Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M.,
RA Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K.,
RA Leather S., Moule S., Mungall K.L., Quail M.A., Rajandream M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G.,
RA Barrell B.G.;
RT "Complete DNA sequence of a serogroup A strain of Neisseria meningitidis
RT Z2491.";
RL Nature 404:502-506(2000).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
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DR EMBL; AL157959; CAM08120.1; -; Genomic_DNA.
DR PIR; H81934; H81934.
DR RefSeq; WP_002229182.1; NC_003116.1.
DR AlphaFoldDB; Q9JVD5; -.
DR SMR; Q9JVD5; -.
DR EnsemblBacteria; CAM08120; CAM08120; NMA0885.
DR GeneID; 83614598; -.
DR KEGG; nma:NMA0885; -.
DR HOGENOM; CLU_087843_4_1_4; -.
DR Proteomes; UP000000626; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; NusB-like; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR NCBIfam; TIGR01951; nusB; 1.
DR PANTHER; PTHR11078:SF3; ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11078; N UTILIZATION SUBSTANCE PROTEIN B-RELATED; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; NusB-like; 1.
PE 3: Inferred from homology;
KW RNA-binding; Transcription; Transcription antitermination;
KW Transcription regulation.
FT CHAIN 1..141
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_0000176558"
SQ SEQUENCE 141 AA; 16049 MW; 89E5B2949A5F0A8D CRC64;
MKTARRRSRE LAVQAVYQSL INRTAAPEIA KNIREMPDFA KADEELFNKL FFGTQTNAAE
YIRQIRPLLD RDEKDLNPIE RAVLLTACHE LSAMPETPYP VIINEAIEVT KTFGGTDGHK
FVNGILDKLA AQIRPDEPKR R
//
