ID O11454_NPVBS Unreviewed; 513 AA.
AC O11454;
DT 01-JUL-1997, integrated into UniProtKB/TrEMBL.
DT 01-JUL-1997, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=Ecdysteroid UDP-glucosyltransferase {ECO:0000256|ARBA:ARBA00013904, ECO:0000256|PIRNR:PIRNR000476};
DE EC=2.4.1.- {ECO:0000256|PIRNR:PIRNR000476};
GN Name=egt {ECO:0000313|EMBL:AAB58353.1};
OS Buzura suppressaria nuclear polyhedrosis virus (BsNPV).
OC Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus;
OC Alphabaculovirus busuppressariae.
OX NCBI_TaxID=74320 {ECO:0000313|EMBL:AAB58353.1};
OH NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN [1] {ECO:0000313|EMBL:AHH82713.1, ECO:0000313|Proteomes:UP000214366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hubei {ECO:0000313|EMBL:AHH82713.1};
RX PubMed=8345353;
RA Hu Z.H., Liu M.F., Jin F., Wang Z.X., Liu X.Y., Li M.J., Liang B.F.,
RA Xie T.E.;
RT "Nucleotide sequence of the Buzura suppressaria single nucleocapsid nuclear
RT polyhedrosis virus polyhedrin gene.";
RL J. Gen. Virol. 74:1617-1620(1993).
RN [2] {ECO:0000313|EMBL:AAB58353.1, ECO:0000313|Proteomes:UP000214366}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hubei {ECO:0000313|EMBL:AHH82713.1};
RX PubMed=9037741; DOI=10.1016/S0168-1702(96)01406-2;
RA Hu Z.H., Broer R., Westerlaken J., Martens J.W., Jin F., Jehle J.A.,
RA Wang L.M., Vlak J.M.;
RT "Characterization of the ecdysteroid UDP-glucosyltransferase gene of a
RT single nucleocapsid nucleopolyhedrovirus of Buzura suppressaria.";
RL Virus Res. 47:91-97(1997).
RN [3] {ECO:0000313|EMBL:AHH82713.1, ECO:0000313|Proteomes:UP000214366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hubei {ECO:0000313|EMBL:AHH82713.1};
RX PubMed=9634101;
RA van Oers M.M., Hu Z., Arif B.M., van Strien E.A., van Lent J.W., Vlak J.M.;
RT "The single-nucleocapsid nucleopolyhedrovirus of Buzura suppressaria
RT encodes a P10 protein.";
RL J. Gen. Virol. 79:1553-1562(1998).
RN [4] {ECO:0000313|EMBL:AHH82713.1, ECO:0000313|Proteomes:UP000214366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hubei {ECO:0000313|EMBL:AHH82713.1};
RX PubMed=9820162;
RA Hu Z.H., Arif B.M., Jin F., Martens J.W., Chen X.W., Sun J.S., Zuidema D.,
RA Goldbach R.W., Vlak J.M.;
RT "Distinct gene arrangement in the Buzura suppressaria single-nucleocapsid
RT nucleopolyhedrovirus genome.";
RL J. Gen. Virol. 79:2841-2851(1998).
RN [5] {ECO:0000313|EMBL:AHH82713.1, ECO:0000313|Proteomes:UP000214366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hubei {ECO:0000313|EMBL:AHH82713.1};
RX PubMed=9712513; DOI=10.1016/S0168-1702(98)00029-X;
RA Hu Z.H., Arif B.M., Sun J.S., Chen X.W., Zuidema D., Goldbach R.W.,
RA Vlak J.M.;
RT "Genetic organization of the HindIII-I region of the single-nucleocapsid
RT nucleopolyhedrovirus of Buzura suppressaria.";
RL Virus Res. 55:71-82(1998).
RN [6] {ECO:0000313|EMBL:AHH82713.1, ECO:0000313|Proteomes:UP000214366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hubei {ECO:0000313|EMBL:AHH82713.1};
RX PubMed=24475121;
RA Zhu Z., Yin F., Liu X., Hou D., Wang J., Zhang L., Arif B., Wang H.,
RA Deng F., Hu Z.;
RT "Genome Sequence and Analysis of Buzura suppressaria Nucleopolyhedrovirus:
RT A Group II Alphabaculovirus.";
RL PLoS ONE 9:E86450-E86450(2014).
RN [7] {ECO:0000313|EMBL:AKN91097.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guangxi {ECO:0000313|EMBL:AKN91097.1};
RA Seo M.-J., Seok Y.J., Cha I.-T.;
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the transfer of glucose from UDP-glucose to
CC ecdysteroids which are insect molting hormones.
CC {ECO:0000256|PIRNR:PIRNR000476}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009995, ECO:0000256|PIRNR:PIRNR000476,
CC ECO:0000256|RuleBase:RU003718}.
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DR EMBL; U61154; AAB58353.1; -; Genomic_DNA.
DR EMBL; KF611977; AHH82713.1; -; Genomic_DNA.
DR EMBL; KM986882; AKN91097.1; -; Genomic_DNA.
DR RefSeq; YP_009001901.1; NC_023442.1.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR GeneID; 18267044; -.
DR KEGG; vg:18267044; -.
DR OrthoDB; 5462at10239; -.
DR Proteomes; UP000214366; Genome.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR InterPro; IPR016224; Ecdysteroid_UDP-Glc_Trfase.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF162; UDP-GLYCOSYLTRANSFERASE FAMILY 305 MEMBER A1, ISOFORM A-RELATED; 1.
DR Pfam; PF00201; UDPGT; 1.
DR PIRSF; PIRSF000476; Ecdystd_UDP_glucosyltfrase; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|PIRNR:PIRNR000476};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000476}.
SQ SEQUENCE 513 AA; 58960 MW; 23FB785D60CDEDC2 CRC64;
MYLLIIFLWL AKQCHGAKIL AVMPTPSYSH QSVFKVYIES LAERGHTIVI IKPTTRVFYD
DRFSDNITEI DATMSEFYFS ELFTNASVFR KRGIVADSKT VTSANYLGLV HMISNQFKLP
AVKQLIEHRH RLQFDVLITE AFIDYPLVFS YLFGDLPIIQ ISSGHGVAEN FETMGAVSRH
PLYYPNMWRD RFTNLNVWET INEIYMEMRL QNEFSLLAEE QNKLLAHQFG IGVPTVQKLR
DRVQLLLVNT HAVFDNNRPV PPSVQYMGGL HLHKKTIKPM SNYVQNFLDN STRGVVYVSF
GSSITSKNMA PEFLSMIIET FKLVPYDIAW KFDIVPEVNN LPENVLIQDW YDQYSVLHHV
NVKVFVTQGG VQSTDEAIDA LVPLVGVPMM GDQFFHTNKY AELSIGCAVD TLTVNSLQLM
RAIVDAATSA KYRNGLRHLR QIINHQPMTP LHKAIWYTEH VIRHGKNDNT WLKTKAANVG
YSDYFMMYIL FPLVSVTAMN QLQQLMRLTF FSM
//
