ID O17504_BOMMO Unreviewed; 146 AA.
AC O17504;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=Multiprotein bridging factor 1 {ECO:0000313|EMBL:BAA21658.1};
GN Name=692355 {ECO:0000313|EnsemblMetazoa:NP_001036824.1};
OS Bombyx mori (Silk moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC Bombycidae; Bombycinae; Bombyx.
OX NCBI_TaxID=7091 {ECO:0000313|EMBL:BAA21658.1};
RN [1] {ECO:0000313|EMBL:BAA21658.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9207077; DOI=10.1073/pnas.94.14.7251;
RA Takemaru K., Li F.Q., Ueda H., Hirose S.;
RT "Multiprotein bridging factor 1 (MBF1) is an evolutionarily conserved
RT transcriptional coactivator that connects a regulatory factor and TATA
RT element-binding protein.";
RL Proc. Natl. Acad. Sci. U.S.A. 94:7251-7256(1997).
RN [2] {ECO:0000313|Proteomes:UP000005204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=p50T {ECO:0000313|Proteomes:UP000005204};
RX PubMed=19121390; DOI=10.1016/j.ibmb.2008.11.004;
RG International Silkworm Genome Consortium;
RT "The genome of a lepidopteran model insect, the silkworm Bombyx mori.";
RL Insect Biochem. Mol. Biol. 38:1036-1045(2008).
RN [3] {ECO:0000313|EnsemblMetazoa:NP_001036824.1}
RP IDENTIFICATION.
RC STRAIN=p50T (Dazao) {ECO:0000313|EnsemblMetazoa:NP_001036824.1};
RG EnsemblMetazoa;
RL Submitted (JUN-2022) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB001078; BAA21658.1; -; mRNA.
DR RefSeq; NP_001036824.1; NM_001043359.1.
DR AlphaFoldDB; O17504; -.
DR SMR; O17504; -.
DR STRING; 7091.O17504; -.
DR PaxDb; 7091-BGIBMGA007702-TA; -.
DR EnsemblMetazoa; NM_001043359.1; NP_001036824.1; GeneID_692355.
DR GeneID; 692355; -.
DR KEGG; bmor:692355; -.
DR CTD; 39842; -.
DR eggNOG; KOG3398; Eukaryota.
DR HOGENOM; CLU_112609_0_1_1; -.
DR InParanoid; O17504; -.
DR OMA; NKAHQGT; -.
DR OrthoDB; 120438at2759; -.
DR Proteomes; UP000005204; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR013729; MBF1_N.
DR PANTHER; PTHR10245:SF15; ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1; 1.
DR PANTHER; PTHR10245; ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF08523; MBF1; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000005204};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 83..133
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT REGION 26..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 146 AA; 16172 MW; 006E5B67399B73B7 CRC64;
MSDWDTVTIL RKKPPKASAL KTEQAVNAAR RQGIPVDTQQ KYGAGTNKQH VTTKNTAKLD
RETEELRHEK IPLDLGKLIM QGRQAKGMSQ KDLATKICEK PQIVNDYEAG RGIPNNIVLG
KIERAIGIKL RGKERGQPLQ PPGGQK
//
