ID O18501_SCHMA Unreviewed; 239 AA.
AC O18501;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 129.
DE RecName: Full=palmitoyl-protein hydrolase {ECO:0000256|ARBA:ARBA00012423};
DE EC=3.1.2.22 {ECO:0000256|ARBA:ARBA00012423};
GN Name=SmLPLH {ECO:0000313|EMBL:AAC62254.1};
OS Schistosoma mansoni (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6183 {ECO:0000313|EMBL:AAC62254.1};
RN [1] {ECO:0000313|EMBL:AAC62254.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9797070; DOI=10.1007/s004360050497;
RA Hamdan F.F., Ribeiro P.;
RT "Cloning and sequence analysis of a lysophospholipase homologue from
RT Schistosoma mansoni.";
RL Parasitol. Res. 84:839-842(1998).
RN [2] {ECO:0000313|Proteomes:UP000008854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA Zerlotini A., Dunne D.W., Berriman M.;
RT "A systematically improved high quality genome and transcriptome of the
RT human blood fluke Schistosoma mansoni.";
RL PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN [3] {ECO:0000313|WBParaSite:Smp_025160.3}
RP IDENTIFICATION.
RC STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_025160.3};
RG WormBaseParasite;
RL Submitted (DEC-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 2
CC family. {ECO:0000256|ARBA:ARBA00006499}.
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DR EMBL; AF006678; AAC62254.1; -; mRNA.
DR RefSeq; XP_018654975.1; XM_018789542.1.
DR STRING; 6183.O18501; -.
DR ESTHER; schma-SmLPLH; LYsophospholipase_carboxylesterase.
DR EnsemblMetazoa; Smp_025160.3; Smp_025160.3; Smp_025160.
DR GeneID; 8352416; -.
DR WBParaSite; Smp_025160.3; Smp_025160.3; Smp_025160.
DR CTD; 8352416; -.
DR eggNOG; KOG2112; Eukaryota.
DR OMA; WYDILAM; -.
DR OrthoDB; 4670340at2759; -.
DR Proteomes; UP000008854; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR003140; PLipase/COase/thioEstase.
DR PANTHER; PTHR10655; LYSOPHOSPHOLIPASE-RELATED; 1.
DR PANTHER; PTHR10655:SF17; PALMITOYL-PROTEIN HYDROLASE; 1.
DR Pfam; PF02230; Abhydrolase_2; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 2: Evidence at transcript level;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000008854}.
FT DOMAIN 20..235
FT /note="Phospholipase/carboxylesterase/thioesterase"
FT /evidence="ECO:0000259|Pfam:PF02230"
SQ SEQUENCE 239 AA; 25870 MW; 8289D6563DC2D441 CRC64;
MGSSISCISE IDMANKLLPA AVVASRSKHS ATLIFLHGLG DTGHGWSDAL KEYVPDYFKI
ICPHANSIPV TLNGGMCMPA WYDIYALSEN AKQDEAGIKE ASLELGKFVD AEIKAGVPIG
NIVIGGFSQG GSVALYNALT STLQYGGVVA FSCWLPLHTK FMSSPTLLTM PKDVPVFQCH
GLEDYTIPFA MGKLTHELLK TFQLSKCELN CYPQLSHSSC EKEMGDLRTF LSKNIPGTQ
//
