ID O25798_HELPY Unreviewed; 202 AA.
AC O25798;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=Carbonic anhydrase {ECO:0000313|EMBL:AAD08232.1};
GN OrderedLocusNames=HP_1186 {ECO:0000313|EMBL:AAD08232.1};
OS Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=85962 {ECO:0000313|EMBL:AAD08232.1, ECO:0000313|Proteomes:UP000000429};
RN [1] {ECO:0000313|EMBL:AAD08232.1, ECO:0000313|Proteomes:UP000000429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700392 / 26695 {ECO:0000313|Proteomes:UP000000429};
RX PubMed=9252185; DOI=10.1038/41483;
RA Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA Fleischmann R.D., Ketchum K.A., Klenk H.P., Gill S., Dougherty B.A.,
RA Nelson K., Quackenbush J., Zhou L., Kirkness E.F., Peterson S., Loftus B.,
RA Richardson D., Dodson R., Khalak H.G., Glodek A., McKenney K.,
RA Fitzegerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D.,
RA Utterback T.R., Peterson J.D., Kelley J.M., Karp P.D., Smith H.O.,
RA Fraser C.M., Venter J.C.;
RT "The complete genome sequence of the gastric pathogen Helicobacter
RT pylori.";
RL Nature 388:539-547(1997).
CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC {ECO:0000256|ARBA:ARBA00010718}.
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DR EMBL; AE000511; AAD08232.1; -; Genomic_DNA.
DR PIR; B64668; B64668.
DR RefSeq; NP_207977.1; NC_000915.1.
DR AlphaFoldDB; O25798; -.
DR SMR; O25798; -.
DR STRING; 85962.HP_1186; -.
DR PaxDb; 85962-C694_06140; -.
DR EnsemblBacteria; AAD08232; AAD08232; HP_1186.
DR KEGG; hpy:HP_1186; -.
DR PATRIC; fig|85962.8.peg.1242; -.
DR eggNOG; COG3338; Bacteria.
DR InParanoid; O25798; -.
DR OrthoDB; 5327615at2; -.
DR PhylomeDB; O25798; -.
DR Proteomes; UP000000429; Chromosome.
DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd03124; alpha_CA_prokaryotic_like; 1.
DR Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR InterPro; IPR041891; Alpha_CA_prokaryot-like.
DR InterPro; IPR001148; CA_dom.
DR InterPro; IPR036398; CA_dom_sf.
DR InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR PANTHER; PTHR18952:SF265; CARBONIC ANHYDRASE; 1.
DR Pfam; PF00194; Carb_anhydrase; 1.
DR SMART; SM01057; Carb_anhydrase; 1.
DR SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR PROSITE; PS51144; ALPHA_CA_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000429};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..202
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004158051"
FT DOMAIN 21..202
FT /note="Alpha-carbonic anhydrase"
FT /evidence="ECO:0000259|PROSITE:PS51144"
SQ SEQUENCE 202 AA; 23216 MW; A16C1472AAEC3D00 CRC64;
MKKTFLIALA LTASLVGAEN TKWDYKNKEN GPHRWDKLHK DFEVCKSGKS QSPINIEHYY
HTQDKADLQF KYAASKPKAV FFTHHTLKAS FEPTNHINYR GHDYVLDNVH FHAPMEFLIN
NKTRPLSAHF VHKDAKGRLL VLAIGFEEGK ENPNLDPILE GIQKKQNFKE VALDAFLPKS
INYYHLTALS PLLLAQRGWH GL
//
