ID O27792_METTH Unreviewed; 444 AA.
AC O27792;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 132.
DE SubName: Full=Sensory transduction regulatory protein {ECO:0000313|EMBL:AAB86230.1};
GN OrderedLocusNames=MTH_1764 {ECO:0000313|EMBL:AAB86230.1};
OS Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX NCBI_TaxID=187420 {ECO:0000313|EMBL:AAB86230.1, ECO:0000313|Proteomes:UP000005223};
RN [1] {ECO:0000313|EMBL:AAB86230.1, ECO:0000313|Proteomes:UP000005223}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H
RC {ECO:0000313|Proteomes:UP000005223};
RX PubMed=9371463;
RA Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA Pietrovski S., Church G.M., Daniels C.J., Mao J.-i., Rice P., Nolling J.,
RA Reeve J.N.;
RT "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT functional analysis and comparative genomics.";
RL J. Bacteriol. 179:7135-7155(1997).
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DR EMBL; AE000666; AAB86230.1; -; Genomic_DNA.
DR PIR; E69102; E69102.
DR AlphaFoldDB; O27792; -.
DR STRING; 187420.MTH_1764; -.
DR PaxDb; 187420-MTH_1764; -.
DR EnsemblBacteria; AAB86230; AAB86230; MTH_1764.
DR KEGG; mth:MTH_1764; -.
DR PATRIC; fig|187420.15.peg.1720; -.
DR HOGENOM; CLU_616260_0_0_2; -.
DR InParanoid; O27792; -.
DR Proteomes; UP000005223; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd17534; REC_DC-like; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44591:SF3; RESPONSE REGULATORY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44591; STRESS RESPONSE REGULATOR PROTEIN 1; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000005223};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 9..124
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 136..194
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 203..255
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT MOD_RES 59
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 444 AA; 50085 MW; 8E957893FDB614D0 CRC64;
MRWTMSRAKV MVVEDESIVA IDISQRLQSL GYEVTATVSS GEKAVEMAEK TRPDIILMDI
VLKGEMGGIE AAEEINKRMK VPIVYITAYS DEETLRRAKV TGPFGYIIKP FEDRELHSVI
EVALYKHELE RRLAENDELF RAILSSVQDI LFTADSEGLL TMVSPGPLAG YGLEADDVLG
KGLVEVFGDE VHHEMIGRAL KGEPVTYEWT WAPHDKFYFE TTLSPLRDFE GNITGVVGIH
RDVTEKETAR RALERETLIN RELADLSKQL LASMSLEEIS DSITRKAEAL TESRYCLAGF
IESGTLKNYT LTENVRRECH LDTDSLKLGG LIEWIMREKE AILLNDPSSD PRYSGVPEDH
VEISNLIAVP AVLRDELVGI LMVSGKEGGY DEGDLELLQR LADIYALAIY RKMEEDRLKA
SEERNRALVE KFLKIVTEVL EEIR
//
