ID O51853_PSEPU Unreviewed; 310 AA.
AC O51853;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JUN-1998, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=3-isopropylcatechol dioxygenase {ECO:0000313|EMBL:AAC03441.1};
GN Name=ipbC {ECO:0000313|EMBL:AAC03441.1};
OS Pseudomonas putida (Arthrobacter siderocapsulatus).
OG Plasmid pRE4 {ECO:0000313|EMBL:AAC03441.1}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=303 {ECO:0000313|EMBL:AAC03441.1};
RN [1] {ECO:0000313|EMBL:AAC03441.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RE204 {ECO:0000313|EMBL:AAC03441.1};
RC PLASMID=pRE4 {ECO:0000313|EMBL:AAC03441.1};
RX PubMed=3019995;
RA Eaton R.W., Timmis K.N.;
RT "Characterization of a plasmid-specified pathway for catabolism of
RT isopropylbenzene in Pseudomonas putida RE204.";
RL J. Bacteriol. 168:123-131(1986).
RN [2] {ECO:0000313|EMBL:AAC03441.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RE204 {ECO:0000313|EMBL:AAC03441.1};
RC PLASMID=pRE4 {ECO:0000313|EMBL:AAC03441.1};
RA Eaton R.W., Selifonova O.V., Gedney R.M.;
RT "Isopropylbenzene catabolic pathway in Pseudomonas putida RE204: sequence
RT analysis of the ipb operon and neighboring DNA from pRE4.";
RL Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954,
CC ECO:0000256|RuleBase:RU000683};
CC -!- SIMILARITY: Belongs to the extradiol ring-cleavage dioxygenase family.
CC {ECO:0000256|ARBA:ARBA00008784, ECO:0000256|RuleBase:RU000683}.
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DR EMBL; AF006691; AAC03441.1; -; Genomic_DNA.
DR AlphaFoldDB; O51853; -.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0008198; F:ferrous iron binding; IEA:InterPro.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0042178; P:xenobiotic catabolic process; IEA:InterPro.
DR CDD; cd07237; BphC1-RGP6_C_like; 1.
DR CDD; cd07252; BphC1-RGP6_N_like; 1.
DR Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 2.
DR InterPro; IPR017626; DiOHbiphenyl_dOase.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR InterPro; IPR037523; VOC.
DR InterPro; IPR000486; Xdiol_ring_cleave_dOase_1/2.
DR NCBIfam; TIGR03213; 23dbph12diox; 1.
DR PANTHER; PTHR21366; GLYOXALASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR21366:SF34; IRON-DEPENDENT EXTRADIOL DIOXYGENASE; 1.
DR Pfam; PF00903; Glyoxalase; 1.
DR SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 2.
DR PROSITE; PS00082; EXTRADIOL_DIOXYGENAS; 1.
DR PROSITE; PS51819; VOC; 2.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797,
KW ECO:0000256|RuleBase:RU000683};
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000256|RuleBase:RU000683};
KW Iron {ECO:0000256|RuleBase:RU000683};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000683}; Plasmid {ECO:0000313|EMBL:AAC03441.1}.
FT DOMAIN 5..119
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
FT DOMAIN 143..278
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
SQ SEQUENCE 310 AA; 34296 MW; C0CCF7E3BF0D7E07 CRC64;
MCIKSLGYMG FSVSDVPAWR SFLSEKVGLM EVSGSDDSAQ YRMDSRSWRI AVQTGEADDI
AFAGYEVANP LALQQMTARL RQAGVQVKTG DTQLAEKRDV MELISFEDPF GMPLEIYYGA
TDYFERPLVS GTGITGFLTG AHGAGHYLYA VPNIEEALAF YTGVLGFQMS DVIDIAMGPN
FTARGYFLHC NGRHHTIAIA EAPLPKRIHH FLLQALTLDD VGHAYDRLDG IGGKTTDSNF
ENSTSSCITA TIGRHVNDHM VSFYAQTPSG FELEFGWGAR DVDDQSWVMT RHKRIAMWGH
KPVRSKSQKS
//
