ID O52206_9ZZZZ Unreviewed; 144 AA.
AC O52206;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JUN-1998, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=MucA {ECO:0000313|EMBL:AAC82517.1};
GN Name=mucA {ECO:0000313|EMBL:AAC82517.1};
OS IncL/M plasmid R446b.
OG Plasmid Unknown {ECO:0000313|EMBL:AAC82517.1}.
OC other sequences; plasmids.
OX NCBI_TaxID=192118 {ECO:0000313|EMBL:AAC82517.1};
RN [1] {ECO:0000313|EMBL:AAC82517.1}
RP NUCLEOTIDE SEQUENCE.
RC PLASMID=Unknown {ECO:0000313|EMBL:AAC82517.1};
RX PubMed=4584057;
RA Hedges R.W., Datta N., Coetzee J.N., Dennison S.;
RT "R factors from Proteus morganii.";
RL J. Gen. Microbiol. 77:249-259(1973).
RN [2] {ECO:0000313|EMBL:AAC82517.1}
RP NUCLEOTIDE SEQUENCE.
RC PLASMID=Unknown {ECO:0000313|EMBL:AAC82517.1};
RX PubMed=8366028;
RA Ho C., Kulaeva O.I., Levine A.S., Woodgate R.;
RT "A rapid method for cloning mutagenic DNA repair genes: isolation of umu-
RT complementing genes from multidrug resistance plasmids R391, R446b, and
RT R471a.";
RL J. Bacteriol. 175:5411-5419(1993).
RN [3] {ECO:0000313|EMBL:AAC82517.1}
RP NUCLEOTIDE SEQUENCE.
RC PLASMID=Unknown {ECO:0000313|EMBL:AAC82517.1};
RX PubMed=9541650; DOI=10.1016/S0027-5107(97)00222-4;
RA Kulaeva O.I., Koonin E.V., Wootton J.C., Levine A.S., Woodgate R.;
RT "Unusual insertion element polymorphisms in the promoter and terminator
RT regions of the mucAB-like genes of R471a and R446b.";
RL Mutat. Res. 397:247-262(1998).
CC -!- SIMILARITY: Belongs to the peptidase S24 family.
CC {ECO:0000256|ARBA:ARBA00007484}.
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DR EMBL; AF027767; AAC82517.1; -; Genomic_DNA.
DR AlphaFoldDB; O52206; -.
DR SMR; O52206; -.
DR MEROPS; S24.003; -.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd06529; S24_LexA-like; 1.
DR Gene3D; 2.10.109.10; Umud Fragment, subunit A; 1.
DR InterPro; IPR039418; LexA-like.
DR InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR InterPro; IPR006197; Peptidase_S24_LexA.
DR InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR PANTHER; PTHR33516; LEXA REPRESSOR; 1.
DR PANTHER; PTHR33516:SF13; PROPHAGE REPRESSOR COHE-RELATED; 1.
DR Pfam; PF00717; Peptidase_S24; 1.
DR PRINTS; PR00726; LEXASERPTASE.
DR SUPFAM; SSF51306; LexA/Signal peptidase; 1.
PE 3: Inferred from homology;
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Plasmid {ECO:0000313|EMBL:AAC82517.1};
KW Protease {ECO:0000256|ARBA:ARBA00022825};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW SOS mutagenesis {ECO:0000256|ARBA:ARBA00023199};
KW SOS response {ECO:0000256|ARBA:ARBA00023236}.
FT DOMAIN 20..132
FT /note="Peptidase S24/S26A/S26B/S26C"
FT /evidence="ECO:0000259|Pfam:PF00717"
SQ SEQUENCE 144 AA; 16107 MW; 78E5BFF5EF7262A0 CRC64;
MALDLVYPRP SVEGDTLPFF AEPVAAGFPS PAAGYEANEL NLHDYCVRRP AATYFLRVSG
DSMRDARIHD GDVLVVDRAE EPRHGSIVIA SIDNEFTVKQ LQLRPYPCLM PLNPAFPPIR
FDPEALQIWG VVTFTVMRHR PCTP
//
