ID O52219_SALTM Unreviewed; 186 AA.
AC O52219; A0A0M2IU35; F1SVL4; Q7DAP3;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JUN-1998, sequence version 1.
DT 27-MAR-2024, entry version 176.
DE SubName: Full=Helix-turn-helix domain-containing protein {ECO:0000313|EMBL:HAB0972698.1};
DE SubName: Full=Putative resolvase {ECO:0000313|EMBL:AOZ60960.1};
DE SubName: Full=Recombinase family protein {ECO:0000313|EMBL:EBU9273818.1};
DE SubName: Full=RlgA {ECO:0000313|EMBL:AAC04696.1};
GN Name=rlgA {ECO:0000313|EMBL:AAC04696.1};
GN Synonyms=RlgA {ECO:0000313|EMBL:BAL48704.1};
GN ORFNames=AVC05_20435 {ECO:0000313|EMBL:ECY5343577.1}, B1P38_23535
GN {ECO:0000313|EMBL:ECU8356488.1}, CE70_23680
GN {ECO:0000313|EMBL:ECE0298111.1}, DMO92_17455
GN {ECO:0000313|EMBL:EBU9273818.1}, DPS76_19055
GN {ECO:0000313|EMBL:EBW5464514.1}, DRM14_21975
GN {ECO:0000313|EMBL:MLP87934.1}, DU071_09320
GN {ECO:0000313|EMBL:EBY1702138.1}, EER35_14555
GN {ECO:0000313|EMBL:EBZ6922180.1}, F3R12_17075
GN {ECO:0000313|EMBL:ECW0641531.1}, GB466_19345
GN {ECO:0000313|EMBL:HAB0972698.1};
OS Salmonella typhimurium.
OG Plasmid pSTV-Mu1 {ECO:0000313|EMBL:AOZ60960.1},
OG Plasmid pYT2 {ECO:0000313|EMBL:BAL48704.1}, and
OG Plasmid virulence {ECO:0000313|EMBL:AAC04696.1}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90371 {ECO:0000313|EMBL:AAC04696.1};
RN [1] {ECO:0000313|EMBL:AAC04696.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LT-2A {ECO:0000313|EMBL:AAC04696.1};
RC PLASMID=virulence {ECO:0000313|EMBL:AAC04696.1};
RA Massey R.C., Sheehan B.J., Dorman C.J.;
RL Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAL48704.1}
RP NUCLEOTIDE SEQUENCE.
RC PLASMID=pYT2 {ECO:0000313|EMBL:BAL48704.1};
RX PubMed=24155970; DOI=10.1371/journal.pone.0077644;
RA Tamamura Y., Tanaka K., Akiba M., Kanno T., Hatama S., Ishihara R.,
RA Uchida I.;
RT "Complete Nucleotide Sequences of Virulence-Resistance Plasmids Carried by
RT Emerging Multidrug-Resistant Salmonella enterica Serovar Typhimurium
RT Isolated from Cattle in Hokkaido, Japan.";
RL PLoS ONE 8:e77644-e77644(2013).
RN [3] {ECO:0000313|EMBL:AOZ60960.1}
RP NUCLEOTIDE SEQUENCE.
RC PLASMID=pSTV-Mu1 {ECO:0000313|EMBL:AOZ60960.1};
RX PubMed=27767038; DOI=10.1038/srep35527;
RA Abraham S., O'Dea M., Trott D.J., Abraham R.J., Hughes D., Pang S.,
RA McKew G., Cheong E.Y., Merlino J., Saputra S., Malik R., Gottlieb T.;
RT "Isolation and plasmid characterization of carbapenemase (IMP-4) producing
RT Salmonella enterica Typhimurium from cats.";
RL Sci. Rep. 6:35527-35527(2016).
RN [4] {ECO:0000313|EMBL:HAB0972698.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Salmonella enterica {ECO:0000313|EMBL:HAB0972698.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [5] {ECO:0000313|EMBL:ECE0298111.1, ECO:0000313|Proteomes:UP000338496}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AUSMDU00020735 {ECO:0000313|EMBL:ECW0641531.1}, and
RC VA_WGS-00080 {ECO:0000313|EMBL:ECE0298111.1,
RC ECO:0000313|Proteomes:UP000338496};
RG GenomeTrakr network: Whole genome sequencing for foodborne pathogen traceback;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:EBY1702138.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=356083 {ECO:0000313|EMBL:EBY1702138.1}, 422529
RC {ECO:0000313|EMBL:EBW5464514.1}, 425567 {ECO:0000313|EMBL:MLP87934.1},
RC 43916 {ECO:0000313|EMBL:ECY5343577.1}, 488670
RC {ECO:0000313|EMBL:EBU9273818.1}, and 632340
RC {ECO:0000313|EMBL:EBZ6922180.1};
RA Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:ECU8356488.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PNUSAS008736 {ECO:0000313|EMBL:ECU8356488.1};
RG PulseNet: The National Subtyping Network for Foodborne Disease Surveillance;
RA Tarr C.L., Trees E., Katz L.S., Carleton-Romer H.A., Stroika S.,
RA Kucerova Z., Roache K.F., Sabol A.L., Besser J., Gerner-Smidt P.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:HAB0972698.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Salmonella enterica {ECO:0000313|EMBL:HAB0972698.1};
RG NCBI Pathogen Detection Project;
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC {ECO:0000256|ARBA:ARBA00009913}.
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DR EMBL; AF029069; AAC04696.1; -; Genomic_DNA.
DR EMBL; KX777254; AOZ60960.1; -; Genomic_DNA.
DR EMBL; AB605179; BAL48704.1; -; Genomic_DNA.
DR EMBL; AAHDPU010000016; EBU9273818.1; -; Genomic_DNA.
DR EMBL; AAHIPE010000024; EBW5464514.1; -; Genomic_DNA.
DR EMBL; AAHNIA010000013; EBY1702138.1; -; Genomic_DNA.
DR EMBL; AAHRYM010000017; EBZ6922180.1; -; Genomic_DNA.
DR EMBL; AAIGQE010000024; ECE0298111.1; -; Genomic_DNA.
DR EMBL; AAKRET010000036; ECU8356488.1; -; Genomic_DNA.
DR EMBL; AAKVET010000014; ECW0641531.1; -; Genomic_DNA.
DR EMBL; AALDNI010000056; ECY5343577.1; -; Genomic_DNA.
DR EMBL; DAAFPQ010000018; HAB0972698.1; -; Genomic_DNA.
DR EMBL; RVDJ01000030; MLP87934.1; -; Genomic_DNA.
DR RefSeq; WP_001240331.1; NZ_WXYU01000026.1.
DR RefSeq; YP_006955259.1; NC_019108.1.
DR RefSeq; YP_006955399.1; NC_019109.1.
DR RefSeq; YP_006955583.1; NC_019001.1.
DR KEGG; seni:CY43_24210; -.
DR PATRIC; fig|90371.1185.peg.5043; -.
DR OMA; RIIYHRV; -.
DR Proteomes; UP000338496; Unassembled WGS sequence.
DR Proteomes; UP000839616; Unassembled WGS sequence.
DR Proteomes; UP000839617; Unassembled WGS sequence.
DR Proteomes; UP000839905; Unassembled WGS sequence.
DR Proteomes; UP000839909; Unassembled WGS sequence.
DR Proteomes; UP000839911; Unassembled WGS sequence.
DR Proteomes; UP000839914; Unassembled WGS sequence.
DR Proteomes; UP000839915; Unassembled WGS sequence.
DR Proteomes; UP000885385; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR CDD; cd03768; SR_ResInv; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.1390; Resolvase, N-terminal catalytic domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006118; Recombinase_CS.
DR InterPro; IPR006119; Resolv_N.
DR InterPro; IPR036162; Resolvase-like_N_sf.
DR InterPro; IPR006120; Resolvase_HTH_dom.
DR PANTHER; PTHR30461; DNA-INVERTASE FROM LAMBDOID PROPHAGE; 1.
DR PANTHER; PTHR30461:SF2; RESOLVASE HOMOLOG YNEB; 1.
DR Pfam; PF02796; HTH_7; 1.
DR Pfam; PF00239; Resolvase; 1.
DR SMART; SM00857; Resolvase; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53041; Resolvase-like; 1.
DR PROSITE; PS00397; RECOMBINASES_1; 1.
DR PROSITE; PS00398; RECOMBINASES_2; 1.
DR PROSITE; PS51736; RECOMBINASES_3; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Plasmid {ECO:0000313|EMBL:AAC04696.1}.
FT DOMAIN 2..136
FT /note="Resolvase/invertase-type recombinase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51736"
FT ACT_SITE 10
FT /note="O-(5'-phospho-DNA)-serine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606118-50,
FT ECO:0000256|PROSITE-ProRule:PRU10137"
SQ SEQUENCE 186 AA; 20587 MW; 6C071235E31317D7 CRC64;
MALYGYARVS TSDQDLTLQT QILRAAGCEI IRAEKASGSG RTGRSELQLL LEFLRPGDTL
MVTRVDRLAR SIKDLQDIVY ALNQQGVTLR ATEQPVDTRS AAGKAFLDML GVFAEFETNL
RRERQMEGIA AAKARGVYRG RKPSIDPAVV YRLYTIEKMG ATAIARQLGI GRASVYRALE
NYEQPA
//
