ID O58820_PYRHO Unreviewed; 371 AA.
AC O58820;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 01-AUG-1998, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=371aa long hypothetical cystathionine gamma-lyase {ECO:0000313|EMBL:BAA30192.1};
GN OrderedLocusNames=PH1093 {ECO:0000313|EMBL:BAA30192.1};
OS Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS 100139 / OT-3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=70601 {ECO:0000313|EMBL:BAA30192.1, ECO:0000313|Proteomes:UP000000752};
RN [1] {ECO:0000313|EMBL:BAA30192.1, ECO:0000313|Proteomes:UP000000752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3
RC {ECO:0000313|Proteomes:UP000000752};
RX PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA Otuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Nakamura Y.,
RA Robb T.F., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT "Complete sequence and gene organization of the genome of a hyper-
RT thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL DNA Res. 5:55-76(1998).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BA000001; BAA30192.1; -; Genomic_DNA.
DR PIR; B71104; B71104.
DR AlphaFoldDB; O58820; -.
DR STRING; 70601.gene:9378052; -.
DR EnsemblBacteria; BAA30192; BAA30192; BAA30192.
DR KEGG; pho:PH1093; -.
DR eggNOG; arCOG00060; Archaea.
DR Proteomes; UP000000752; Chromosome.
DR GO; GO:0016846; F:carbon-sulfur lyase activity; IEA:UniProt.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF15; CYSTATHIONINE GAMMA-LYASE; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
SQ SEQUENCE 371 AA; 41927 MW; 301658484593E4B9 CRC64;
MARLKPLHEP LYLTAVFRQV GEAYLTPRNT ELKYSREENP TVLNLENKLA KLEGADNALA
FNSGIAAIAT LYFSFLEAGD EAVLSMEGYG TTIELARLIG RRFGVKIRLA YPRAEDIVEE
INERTKLVLI ETMTNPTLKV IDVREVAKRC REVETILVVD NTFVTPLLYK PLKDGANFVV
HSLTKYIAGH NDVLGGAILW NGEFIHDLWN WRRRLGGIIQ PFDAWMIERG MRTLEVRFER
QSKNAQAIAE FLSEHPKVKE VHYPGLEDDP YHEIAKKLFE RDLYGGVVSF DVGNESNAIV
FLRSIKKIFP SPSLGGVESI VTYPVKSAAR YINEEQREAL GITEGLIRLS VGLEPLDELL
EDLDKALEVV K
//
