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Database: UniProt
Entry: O66495_AQUAE
LinkDB: O66495_AQUAE
Original site: O66495_AQUAE 
ID   O66495_AQUAE            Unreviewed;       338 AA.
AC   O66495;
DT   01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT   01-AUG-1998, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   RecName: Full=EAL domain-containing protein {ECO:0000259|PROSITE:PS50883};
GN   OrderedLocusNames=aq_083 {ECO:0000313|EMBL:AAC06454.1};
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324 {ECO:0000313|EMBL:AAC06454.1, ECO:0000313|Proteomes:UP000000798};
RN   [1] {ECO:0000313|EMBL:AAC06454.1, ECO:0000313|Proteomes:UP000000798}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5 {ECO:0000313|EMBL:AAC06454.1,
RC   ECO:0000313|Proteomes:UP000000798};
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olson G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
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DR   EMBL; AE000657; AAC06454.1; -; Genomic_DNA.
DR   PIR; D70308; D70308.
DR   RefSeq; NP_213055.1; NC_000918.1.
DR   RefSeq; WP_010879993.1; NC_000918.1.
DR   AlphaFoldDB; O66495; -.
DR   STRING; 224324.aq_083; -.
DR   EnsemblBacteria; AAC06454; AAC06454; aq_083.
DR   KEGG; aae:aq_083; -.
DR   PATRIC; fig|224324.8.peg.73; -.
DR   eggNOG; COG2200; Bacteria.
DR   HOGENOM; CLU_000445_70_0_0; -.
DR   InParanoid; O66495; -.
DR   OrthoDB; 7057390at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   CDD; cd01948; EAL; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF78; CYCLIC DI-GMP PHOSPHODIESTERASE PDEI-RELATED; 1.
DR   Pfam; PF00563; EAL; 1.
DR   SMART; SM00052; EAL; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   PROSITE; PS50883; EAL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000798}.
FT   DOMAIN          85..330
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   338 AA;  38784 MW;  F9DF437F8B421A8A CRC64;
     MEEILFLFKD EEKAREFEES LHSTGAKTRR TGTAVITAGL KDEEILYLLS EMDENTLKDL
     KVYQGEVGND CENIVKAISK AEPVTNLIDK VIYHSLGNIF IDTKTLFHPI VDVKEKRVKA
     FEALCRPPIK IVDLINMGKS TSEFSENFCR YMALKNARKF LKEDMWLFLN FHPRFLREPL
     KVFGDFISTL YMHDVSPRQV VVELTEYEEL EISAVKSLIS FLKSEGVKIA LDDVGSGYSG
     LFYLSELGPD IIKIDMELIR DIHKHSMKKV IVNYLIRLAH ENNIKVVSEG VETLEELKTV
     LYMGTDFVQG FIFSKPLENP NLEELNEKIE KIISQSLT
//
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