ID   O71240_9HIV1            Unreviewed;        62 AA.
AC   O71240;
DT   01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT   01-AUG-1998, sequence version 1.
DT   13-SEP-2023, entry version 58.
DE   SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:AAC05969.1};
DE   Flags: Fragment;
GN   Name=pol {ECO:0000313|EMBL:AAC05969.1};
OS   Human immunodeficiency virus 1.
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=11676 {ECO:0000313|EMBL:AAC05969.1};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1] {ECO:0000313|EMBL:AAC05969.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=9499103;
RA   Gunthard H.F., Wong J.K., Ignacio C.C., Guatelli J.C., Riggs N.L.,
RA   Havlir D.V., Richman D.D.;
RT   "Human immunodeficiency virus replication and genotypic resistance in blood
RT   and lymph nodes after a year of potent antiretroviral therapy.";
RL   J. Virol. 72:2422-2428(1998).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF040624; AAC05969.1; -; Genomic_RNA.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918,
KW   ECO:0000313|EMBL:AAC05969.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..62
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAC05969.1"
FT   NON_TER         62
FT                   /evidence="ECO:0000313|EMBL:AAC05969.1"
SQ   SEQUENCE   62 AA;  7477 MW;  E5CA65C36B57108D CRC64;
     FQSSMTKILE PFRKQNPDIV IYQYMDDLYV GSDLEIGQHR AKIEELREHL LRWGFDTPDK
     KH
//