ID O76114_PLAFA Unreviewed; 559 AA.
AC O76114;
DT 01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1998, sequence version 1.
DT 22-FEB-2023, entry version 53.
DE SubName: Full=Thrombospondin-related protein {ECO:0000313|EMBL:BAA31173.1};
DE Flags: Fragment;
OS Plasmodium falciparum (malaria parasite P. falciparum).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5833 {ECO:0000313|EMBL:BAA31173.1};
RN [1] {ECO:0000313|EMBL:BAA31173.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9657338; DOI=10.1016/S0166-6851(98)00004-8;
RA Jongwutiwes S., Putaporntip C., Kanbara H., Tanabe K.;
RT "Variation in the thrombospondin-related adhesive protein (TRAP) gene of
RT Plasmodium falciparum from Thai field isolates.";
RL Mol. Biochem. Parasitol. 92:349-353(1998).
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DR EMBL; AB006337; BAA31173.1; -; Genomic_DNA.
DR AlphaFoldDB; O76114; -.
DR VEuPathDB; PlasmoDB:PfIT_130041200; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01471; vWA_micronemal_protein; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR16059; ANTHRAX TOXIN RECEPTOR; 1.
DR PANTHER; PTHR16059:SF25; THROMBOSPONDIN-RELATED ANONYMOUS PROTEIN; 1.
DR Pfam; PF00090; TSP_1; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00209; TSP1; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50092; TSP1; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..559
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004160563"
FT DOMAIN 48..234
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 279..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..405
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 559
FT /evidence="ECO:0000313|EMBL:BAA31173.1"
SQ SEQUENCE 559 AA; 63314 MW; 1D463C5BF5B8C248 CRC64;
MNHLGNVKYL VIVFLIFFDL FLVNGRDVQN NIVDEIKYRE EVCNDEVDLY LLMDCSGSYR
RHNWVNHAVP LAMKLIQQLN LNENAIHLYL NDFSNNAREI IRLHSDASKN KEKALIIIKS
LLSTNLPYGR TNLSDALLQV RKHLNDRINR ENANQLVVIL TDGIPDSIQD SLKESRKLND
RGVKIAVFGI GQGINVAFNR FLVGCHPSDG KCNLYADSAW ENVKNVIGPF MKAVCVEVEK
TASCGVWDEW SPCSVTCGKG TRSRKREILH EGCTSEIQEQ CEEERCPPKR EPLDVPHEPE
DDQPRPRGDN FAVEKPKENI IDNNPQEPSP NPEEGKGENP NGFDLDENPE NPPNPDIPEQ
EPNIPEDSEK EVPSDVPKNP EDDREENFDI PKKPENKHDN QNNLPNDKSD RSIPYSPLPP
KVLDNERKQS DPQSQDNNGN RHVPNSEDRE TRPHGRNNEN RSYNRKHNNT PKHPEREEHE
KPDNNKKKGG SDNKYKIAGG IAGGLALLAS AGLAYKFVVP GAATPYAGEP APFDETLGEE
DKDLDEPEQF RLPEENEWN
//
