ID O76115_PLAFA Unreviewed; 565 AA.
AC O76115;
DT 01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1998, sequence version 1.
DT 22-FEB-2023, entry version 54.
DE SubName: Full=Thrombospondin-related protein {ECO:0000313|EMBL:BAA31175.1};
DE Flags: Fragment;
OS Plasmodium falciparum (malaria parasite P. falciparum).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5833 {ECO:0000313|EMBL:BAA31175.1};
RN [1] {ECO:0000313|EMBL:BAA31175.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9657338; DOI=10.1016/S0166-6851(98)00004-8;
RA Jongwutiwes S., Putaporntip C., Kanbara H., Tanabe K.;
RT "Variation in the thrombospondin-related adhesive protein (TRAP) gene of
RT Plasmodium falciparum from Thai field isolates.";
RL Mol. Biochem. Parasitol. 92:349-353(1998).
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DR EMBL; AB006339; BAA31175.1; -; Genomic_DNA.
DR AlphaFoldDB; O76115; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01471; vWA_micronemal_protein; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR16059; ANTHRAX TOXIN RECEPTOR; 1.
DR PANTHER; PTHR16059:SF25; THROMBOSPONDIN-RELATED ANONYMOUS PROTEIN; 1.
DR Pfam; PF00090; TSP_1; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00209; TSP1; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50092; TSP1; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..565
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004159751"
FT DOMAIN 48..234
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 279..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..366
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..411
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..565
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 565
FT /evidence="ECO:0000313|EMBL:BAA31175.1"
SQ SEQUENCE 565 AA; 63936 MW; C1A2DB4FB35677F1 CRC64;
MNHLGNVKYL VIVFLIFFDL FLVNGRDVQN NIVDEIKYRE EVCNDEVDLY LLMDCSGSYR
RHNWVNHAVP LAMKLIQQLN LNESAIHLYV NVFSNNAKEI IRLHSDASKN KEKALIIIRS
LLSTNLPYGR TNLTDALLQV RKHLNDRINR ENANQLVVIL TDGIPDSIQD SLKESRKLND
RGVKIAVFGI GQGINVAFNR FLVGCHPSDG KCNLYADSAW ENVKNVIGPF MKAVCVEVEK
TASCGVWDEW SPCSVTCGKG TRSRKREILH EGCTSELQEQ CEEERCPPKR EPLDVPHEPE
DDQPRPRGDN FAFEKPEENI IDNNPQEPSP NPEEGKGENP NGFDLDENPE NPPNPPNPPN
PDIPQQEPNI PEDSEKEVPS DVPKNPEDDR EENFDIPKKP ENKHDNQNNL PNDKSDRSIP
YSPLPPKVLD NERKQSDPQS QDNNGNRHVP NSEDRETRPH GRNNENRSYN RKHNNTPKHP
EREEHEKPDN NKQKGGSDNK YKIAGGIAGG LALLASAGLA YKFVVPGAAT PYAGEPAPFD
ETLGEEDKDL DEPEQFRLPE ENEWN
//
