ID O82460_LOTJA Unreviewed; 432 AA.
AC O82460;
DT 01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1998, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Rac GTPase activating protein 3 {ECO:0000313|EMBL:AAC62626.1};
DE Flags: Fragment;
OS Lotus japonicus (Lotus corniculatus var. japonicus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; robinioid clade; Loteae; Lotus.
OX NCBI_TaxID=34305 {ECO:0000313|EMBL:AAC62626.1};
RN [1] {ECO:0000313|EMBL:AAC62626.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Gifu B-129 {ECO:0000313|EMBL:AAC62626.1};
RC TISSUE=Rhizobium loti infected roots and root nodules
RC {ECO:0000313|EMBL:AAC62626.1};
RX PubMed=10405172; DOI=10.1016/S0014-5793(99)00750-4;
RA Borg S., Podenphant L., Jensen T.J., Poulsen C.;
RT "Plant cell growth and differentiation may involve GAP regulation of Rac
RT activity.";
RL FEBS Lett. 453:341-345(1999).
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DR EMBL; AF064789; AAC62626.1; -; mRNA.
DR AlphaFoldDB; O82460; -.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 3.90.810.10; CRIB domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR044785; RopGAP1-5.
DR PANTHER; PTHR23177; MKIAA1688 PROTEIN; 1.
DR PANTHER; PTHR23177:SF62; PAK-BOX_P21-RHO-BINDING DOMAIN RHO GTPASE ACTIVATING PROTEIN; 1.
DR Pfam; PF00786; PBD; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00285; PBD; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50108; CRIB; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 42..55
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT DOMAIN 87..268
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 272..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAC62626.1"
SQ SEQUENCE 432 AA; 47075 MW; F13A2ADE1C95BB5C CRC64;
EEAEQNQGSP AAFLLAALKK SMVACSVDSP DDVISAVHPM EIGWPTNVKH VTHVTFDRFN
GFLGLPLELE VHVPAPVPSA SVSVFGVSAE SMHCSYDSKG NSVPTILLLM QERLYSQGGL
MAEGIFRINP ENGQEEHLRD QLNRGVVPDN IDVHCLAGLI KAWFRELPSG VLDGLSPEQV
LECNTEEEFV QLVKQLKPTE LALLNWALDL MADVVEEEEH NKMDARNIAM VFAPNMTQMS
DPLTALMHAV QVMNLLKTLI LKTLSEREEA TTAGYSSMSS HSSDRQSEDE YDSQLEMYTS
AELRGSQSDC DDHVNNNSLN SEEEVDSASV SEIEECFLKQ LNENKQGGFA EEPARSTCSG
YNLESAVSFT DAKPDNSCSS SYEDDSGATL SAEGSSAESS SPSIGSTYCT NDVEMMDKFA
DCVSLVPLFA SS
//
