ID O86527_STRCO Unreviewed; 261 AA.
AC O86527;
DT 01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1998, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE RecName: Full=Fumarylacetoacetate hydrolase family protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=SCO5546 {ECO:0000313|EMBL:CAA19994.1};
GN ORFNames=SC1C2.27 {ECO:0000313|EMBL:CAA19994.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAA19994.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAA19994.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
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DR EMBL; AL939124; CAA19994.1; -; Genomic_DNA.
DR PIR; T29076; T29076.
DR RefSeq; NP_629680.1; NC_003888.3.
DR RefSeq; WP_003973449.1; NZ_VNID01000011.1.
DR AlphaFoldDB; O86527; -.
DR STRING; 100226.gene:17763198; -.
DR PaxDb; 100226-SCO5546; -.
DR PATRIC; fig|100226.15.peg.5634; -.
DR eggNOG; COG0179; Bacteria.
DR HOGENOM; CLU_028458_4_2_11; -.
DR InParanoid; O86527; -.
DR OrthoDB; 9805307at2; -.
DR PhylomeDB; O86527; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0018773; F:acetylpyruvate hydrolase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.370; FAH; 1.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR InterPro; IPR018833; Rv2993c-like_N.
DR PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR PANTHER; PTHR11820:SF7; ACYLPYRUVASE FAHD1, MITOCHONDRIAL; 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR Pfam; PF10370; Rv2993c-like_N; 1.
DR SUPFAM; SSF56529; FAH; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT DOMAIN 1..55
FT /note="Rv2993c-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10370"
FT DOMAIN 60..258
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
SQ SEQUENCE 261 AA; 28189 MW; F4383186C3D6F49E CRC64;
MRIARFSIDG NVAFGAVEGD QPDQLVLDII KGIPFADYEL SGTKVPLSKV RLLPPVLPSK
VVAFGRNYAE HARELGNEVP DAPFAFFKPS TSVIGPGDAV QYPSFTEELH HEAELAVVIG
RMCREVPRER VQDVIFGYTC ANDITARDVQ RREKQWARAK GFDSSCPLGP WVETDLDLAA
AGDLTVQLTV NGAQRQLGRT SEMIHSIEDL IVNISEAMTL LPGDVILTGT PAGVGPLNVG
DEVAVTIEGI GTLTNKVVKR G
//
