ID OPGH_SHEB8 Reviewed; 727 AA.
AC A6WMM7;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072};
GN OrderedLocusNames=Shew185_1923;
OS Shewanella baltica (strain OS185).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=402882;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OS185;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C.,
RA Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Brettar I., Rodrigues J., Konstantinidis K., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Shewanella baltica OS185.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01072}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR EMBL; CP000753; ABS08066.1; -; Genomic_DNA.
DR RefSeq; WP_006086416.1; NC_009665.1.
DR AlphaFoldDB; A6WMM7; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR GeneID; 11772130; -.
DR KEGG; sbm:Shew185_1923; -.
DR HOGENOM; CLU_015730_1_0_6; -.
DR UniPathway; UPA00637; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd04191; Glucan_BSP_MdoH; 1.
DR HAMAP; MF_01072; MdoH_OpgH; 1.
DR InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF5; GLUCANS BIOSYNTHESIS GLUCOSYLTRANSFERASE H; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..727
FT /note="Glucans biosynthesis glucosyltransferase H"
FT /id="PRO_1000084501"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 408..428
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 460..480
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 496..516
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 572..592
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT REGION 18..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 81031 MW; F6F3810EC6C73AD9 CRC64;
MTVSENSVLE TEVLVGGSAM PNERPGAMEP QNLSKMPEGF PRRSTVANGV RSRASRRFLV
VGGALLLSLF AIYEMGAVFS IGGITPLEYL VLALFAVNFC WIALAFCSGI AGFLILLRKP
RAKDLQVTEL HTRTAILMPT YNESPDRVFS AVSVMAETLS QTGHGHAFDW FILSDTTDPD
IALLEEQAFL VLRQETHKHS RVYYRRRRKN VARKAGNVAD FCRRWGSRYD HLLVLDADSL
MESSTITGLA QRMQADPDAG LIQTIPSLIN GTTLMARLQQ FAARIYGPVI GTGLGWWVQK
EGNFWGHNAI IRTEAFMTAA GLPNLKGKPP FGGHIMSHDF VEAALIRRAG WSVVIAYDLP
GSYEECPPSI IDLAVRDRRW CQGNLQHSRI LPTKGLHWVS RLHLLTGIMA YLSSPFWLML
ILTGLMLALQ AHFIRPEYFT DQFSLFPTWP IMDSDRALRL FYITMGVLFG PKVFGVLLLL
KDGEFARSVG GRIKAIFSVI FEVILSALIA PIMMFIHCGA VMSILMGRDS GWSPQRRDDG
SMPWMTLIYR HRWHMLAGVM LGYAAILDSL TLLAWMSPAL IGLWIAVPIS AWTGSVKIGE
VFKRAGILAT PEERNPAQIC LQAHEARAAY QKHIAEPWTL AQVLKDPALM ELHLAMVDKQ
PLRAAGTPIE AMEAIVHVKV HEARCQQSAL AVLNRQEMAM VLANPLMLRS LQKLPEQFVE
EDLVSFC
//
