ID P77568_PSEAI Unreviewed; 358 AA.
AC P77568; A0A1S1C0I2; Q51421; Q7DC43;
DT 01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT 01-FEB-1997, sequence version 1.
DT 27-MAR-2024, entry version 158.
DE SubName: Full=AlgZ {ECO:0000313|EMBL:AAB08056.1, ECO:0000313|EMBL:QJE81865.1};
DE SubName: Full=FimS {ECO:0000313|EMBL:AAA88426.2, ECO:0000313|EMBL:OTI65709.1};
DE EC=2.7.13.3 {ECO:0000313|EMBL:CRO14529.1, ECO:0000313|EMBL:VFT42433.1};
DE SubName: Full=Sensor histidine kinase {ECO:0000313|EMBL:CRO14529.1, ECO:0000313|EMBL:MUI35861.1};
GN Name=algZ {ECO:0000313|EMBL:AAB08056.1};
GN Synonyms=fimS {ECO:0000313|EMBL:AAA88426.2}, lytS
GN {ECO:0000313|EMBL:QJE81865.1}, yehU {ECO:0000313|EMBL:CRO14529.1};
GN ORFNames=CAZ10_00060 {ECO:0000313|EMBL:OTI65709.1}, DT376_19670
GN {ECO:0000313|EMBL:RCI73187.1}, GNQ48_12650
GN {ECO:0000313|EMBL:MUI35861.1}, GUL26_21995
GN {ECO:0000313|EMBL:MZZ14927.1}, NCTC13621_05318
GN {ECO:0000313|EMBL:VFT42433.1}, PA52Ts2_0460
GN {ECO:0000313|EMBL:QJE81865.1}, PAERUG_P19_London_7_VIM_2_05_10_00911
GN {ECO:0000313|EMBL:CRO14529.1};
OS Pseudomonas aeruginosa.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=287 {ECO:0000313|EMBL:AAB08056.1};
RN [1] {ECO:0000313|EMBL:AAA88426.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PAO1 {ECO:0000313|EMBL:AAA88426.2};
RX PubMed=8790418; DOI=10.1073/pnas.93.18.9839;
RA Whitchurch C.B., Alm R.A., Mattick J.S.;
RT "The alginate regulator AlgR and an associated sensor FimS are required for
RT twitching motility in Pseudomonas aeruginosa.";
RL Proc. Natl. Acad. Sci. U.S.A. 93:9839-9843(1996).
RN [2] {ECO:0000313|EMBL:AAB08056.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PAO568 {ECO:0000313|EMBL:AAB08056.1};
RA Yu H., Mudd M., Deretic V.;
RL Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAC44751.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PAO1 {ECO:0000313|EMBL:AAC44751.1};
RX PubMed=8981997;
RA Yu H., Mudd M., Boucher J.C., Schurr M.J., Deretic V.;
RT "Identification of the algZ gene upstream of the response regulator algR
RT and its participation in control of alginate production in Pseudomonas
RT aeruginosa.";
RL J. Bacteriol. 179:187-193(1997).
RN [4] {ECO:0000313|EMBL:AAA88426.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PAO1 {ECO:0000313|EMBL:AAA88426.2};
RA Whitchurch C.;
RL Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Proteomes:UP000045039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P19_London_7_VIM_2_05_10 {ECO:0000313|Proteomes:UP000045039};
RA Radhakrishnan Rajesh, Underwood Anthony, Al-Shahib Ali;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:CRO14529.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=P19_London_7_VIM_2_05_10 {ECO:0000313|EMBL:CRO14529.1};
RA Radhakrishnan R., Underwood A., Al-Shahib A.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:OTI65709.1, ECO:0000313|Proteomes:UP000194857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S567_C10_BS {ECO:0000313|EMBL:OTI65709.1,
RC ECO:0000313|Proteomes:UP000194857};
RA Song R., Chenine A.L., Ruprecht R.M.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:RCI73187.1, ECO:0000313|Proteomes:UP000253594}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B2-305 {ECO:0000313|EMBL:RCI73187.1,
RC ECO:0000313|Proteomes:UP000253594};
RA Ballaben A.S., Darini A.L.C., Doi Y.;
RT "Mechanisms of high-level aminoglycoside resistance among Gram-negative
RT pathogens in Brazil.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [9] {ECO:0000313|EMBL:VFT42433.1, ECO:0000313|Proteomes:UP000344659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13621 {ECO:0000313|EMBL:VFT42433.1,
RC ECO:0000313|Proteomes:UP000344659};
RG Pathogen Informatics;
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|EMBL:MUI35861.1, ECO:0000313|Proteomes:UP000433532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PA221 {ECO:0000313|EMBL:MUI35861.1,
RC ECO:0000313|Proteomes:UP000433532};
RA Khan M., Rice S.A., Willcox M.D.P., Stapleton F.;
RT "Genomes of ocular Pseudomonas aeruginosa isolates.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
RN [11] {ECO:0000313|EMBL:MZZ14927.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VNMU148 {ECO:0000313|EMBL:MZZ14927.1};
RA Snesrud E., Galac M.R., Mc Gann P., Valentine K., Viacheslav K.;
RT "Bacteria Cultured from War Wounds Associated with the Conflict in Eastern
RT Ukraine.";
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
RN [12] {ECO:0000313|EMBL:QJE81865.1, ECO:0000313|Proteomes:UP000502341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GIMC5020:PA52Ts2 {ECO:0000313|EMBL:QJE81865.1,
RC ECO:0000313|Proteomes:UP000502341};
RA Voronina O.L., Kunda M.S., Aksenova E.I., Ryzhova N.N., Semenov A.N.;
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; L48729; AAA88426.2; -; Genomic_DNA.
DR EMBL; U52431; AAB08056.1; -; Genomic_DNA.
DR EMBL; U50713; AAC44751.1; -; Genomic_DNA.
DR EMBL; CVVU01000034; CRO14529.1; -; Genomic_DNA.
DR EMBL; WOAD01000008; MUI35861.1; -; Genomic_DNA.
DR EMBL; WXZT01000015; MZZ14927.1; -; Genomic_DNA.
DR EMBL; NFFZ01000001; OTI65709.1; -; Genomic_DNA.
DR EMBL; CP051768; QJE81865.1; -; Genomic_DNA.
DR EMBL; QORE01000687; RCI73187.1; -; Genomic_DNA.
DR EMBL; CAADJP010000010; VFT42433.1; -; Genomic_DNA.
DR PIR; D82989; D82989.
DR RefSeq; NP_253949.1; NC_002516.2.
DR RefSeq; WP_003096404.1; NZ_WYAF01000006.1.
DR DNASU; 879635; -.
DR GeneID; 879635; -.
DR KEGG; pae:PA5262; -.
DR PATRIC; fig|287.1477.peg.5727; -.
DR OMA; NSMNTIA; -.
DR PHI-base; PHI:8157; -.
DR Proteomes; UP000045039; Unassembled WGS sequence.
DR Proteomes; UP000194857; Unassembled WGS sequence.
DR Proteomes; UP000253594; Unassembled WGS sequence.
DR Proteomes; UP000344659; Unassembled WGS sequence.
DR Proteomes; UP000433532; Unassembled WGS sequence.
DR Proteomes; UP000502341; Chromosome.
DR Proteomes; UP000644192; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043107; P:type IV pilus-dependent motility; IMP:CACAO.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF06580; His_kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CRO14529.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:CRO14529.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 163..241
FT /note="Signal transduction histidine kinase internal
FT region"
FT /evidence="ECO:0000259|Pfam:PF06580"
SQ SEQUENCE 358 AA; 40112 MW; 422E53F1F0F17087 CRC64;
MPIRFKPGRS TRPAVQDDFF IPELCEAEAL FTLVLLAELL VLVLVLAEPM TPSFNWVRLA
LASLFVQWIV LLSAALFCRL RPLLARLPVA LAGSACCLLV VALTLGCTAV AEHYQLGGEL
TRAGEVNLYL RHALIALIMS ALVLRYFYLQ SQWRRQQQAE LQARLESLQA RIRPHFLFNS
LNSIASLIEL DPLKAEHAVL DLSDLFRASL AKPGTLVSWE EELALARRYL SIEQYRLGDR
LQLDWQVHGV PANLPIPQLT LQPLLENALI YGIQPRVEGG LVQVEAVYRE GVFQLCVSNP
YDEALESPPS KGTRQALHNI DARLGALFGP KASLSVERRD GRHYTCLRYP CARLMQEA
//
