ID P94901_LEGPN Unreviewed; 575 AA.
AC P94901; E1XY07;
DT 01-MAY-1997, integrated into UniProtKB/TrEMBL.
DT 01-MAY-1997, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=FrgA {ECO:0000313|EMBL:AAC44717.1};
DE SubName: Full=Siderophore biosynthesis protein {ECO:0000313|EMBL:TIE44733.1};
GN Name=frgA {ECO:0000313|EMBL:AAC44717.1};
GN ORFNames=DIZ50_14000 {ECO:0000313|EMBL:TIE44733.1};
OS Legionella pneumophila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=446 {ECO:0000313|EMBL:AAC44717.1};
RN [1] {ECO:0000313|EMBL:AAC44717.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Wadsworth 130b {ECO:0000313|EMBL:AAC44717.1};
RX PubMed=8975903;
RA Hickey E.K., Cianciotto N.P.;
RT "An iron- and fur-repressed Legionella pneumophila gene that promotes
RT intracellular infection and encodes a protein with similarity to the
RT Escherichia coli aerobactin synthetases.";
RL Infect. Immun. 65:133-143(1997).
RN [2] {ECO:0000313|EMBL:TIE44733.1, ECO:0000313|Proteomes:UP000309706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=POC1 {ECO:0000313|EMBL:TIE44733.1,
RC ECO:0000313|Proteomes:UP000309706};
RA Garner E.;
RT "Whole genome sequence comparison of clinical and drinking water Legionella
RT pneumophila isolates.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IucA/IucC family.
CC {ECO:0000256|ARBA:ARBA00007832}.
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DR EMBL; U76559; AAC44717.1; -; Genomic_DNA.
DR EMBL; QFHM01000012; TIE44733.1; -; Genomic_DNA.
DR RefSeq; WP_038839772.1; NZ_UGOS01000001.1.
DR AlphaFoldDB; P94901; -.
DR Proteomes; UP000309706; Unassembled WGS sequence.
DR GO; GO:0016881; F:acid-amino acid ligase activity; IEA:UniProt.
DR GO; GO:0019290; P:siderophore biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.510.40; -; 1.
DR InterPro; IPR007310; Aerobactin_biosyn_IucA/IucC_N.
DR InterPro; IPR022770; IucA/IucC-like_C.
DR InterPro; IPR037455; LucA/IucC-like.
DR PANTHER; PTHR34384; L-2,3-DIAMINOPROPANOATE--CITRATE LIGASE; 1.
DR PANTHER; PTHR34384:SF5; L-2,3-DIAMINOPROPANOATE--CITRATE LIGASE; 1.
DR Pfam; PF06276; FhuF; 1.
DR Pfam; PF04183; IucA_IucC; 1.
PE 3: Inferred from homology;
FT DOMAIN 140..374
FT /note="Aerobactin siderophore biosynthesis IucA/IucC N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF04183"
FT DOMAIN 398..557
FT /note="Aerobactin siderophore biosynthesis IucA/IucC-like
FT C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06276"
SQ SEQUENCE 575 AA; 67117 MW; 2774EB0D8E0A7101 CRC64;
MALAYGNFHE LSHQLRFLLF EIGIGLPQNS VDYFITLAHK NTLKRLQHAS IKEGLIQSAI
ASHHIHDFID QLQIKLKNSM PESKFFQWRK IREALDESIA NEALAYAYRQ NWNTQLRNEA
MHYKSLWTWI NNELSPYQTL LFLEQWGSLR HPYHPAFSAK TGFTRREVLQ NSPEFQAKVS
VHWCALNKTK IQSISPKIDY ANQISQEFPK EYFYWREKLL FSHINPDDYY PIPVHPWQWR
NQLQMAFASL IDNKSLILLP HHQTLIPSLS PDIMMPTQST QCTLKLATTL STSMAGKLDN
SNDMVLLTRW IDSLLAKTNY YQNTLFICKN LESMSAYDQT LSECNRVKLL FGLYQNPLHK
IRQDQRAVPL PALLTDSPCS NTPLLIEIIK ASGLHPTTYF TEYCYKMLFG QLHLLLKYGL
ALEVEQHNIL VIFDDNKPQG IIIKEPNNLK LCNHELFKNV QKPNAPDSLS IYTKDLNQVR
TLFIQGTLKN HLHHLIGCLR NEYQIPSRTL WGLARQVMQT VFKDLSKDID PRILSWQQHL
LLHDNWEHQP ELLLSLHSKI NRNITIKEYN PLSEI
//
