ID P94950_9EURY Unreviewed; 224 AA.
AC P94950; Q7LWX0;
DT 01-MAY-1997, integrated into UniProtKB/TrEMBL.
DT 01-JUL-1997, sequence version 2.
DT 24-JAN-2024, entry version 88.
DE RecName: Full=THIF-type NAD/FAD binding fold domain-containing protein {ECO:0000259|Pfam:PF00899};
GN ORFNames=HA336_06450 {ECO:0000313|EMBL:HII70853.1};
OS Methanopyrus kandleri.
OC Archaea; Euryarchaeota; Methanomada group; Methanopyri; Methanopyrales;
OC Methanopyraceae; Methanopyrus.
OX NCBI_TaxID=2320 {ECO:0000313|EMBL:CAA71297.1};
RN [1] {ECO:0000313|EMBL:CAA71297.1}
RP NUCLEOTIDE SEQUENCE.
RA Klein A.;
RL Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAA71297.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9151968; DOI=10.1111/j.1432-1033.1997.t01-1-00386.x;
RA Klein A.R., Thauer R.K.;
RT "Overexpression of the coenzyme-F420-dependent N5,N10-
RT methylenetetrahydromethanopterin dehydrogenase gene from the
RT hyperthermophilic Methanopyrus kandleri.";
RL Eur. J. Biochem. 245:386-391(1997).
RN [3] {ECO:0000313|EMBL:HII70853.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UBA8853 {ECO:0000313|EMBL:HII70853.1};
RX DOI=10.1101/2020.03.01.972265;
RA Rinke C., Chuvochina M., Mussig A.J., Chaumeil P.-A., Waite D.W.,
RA Whitman W.B., Parks D.H., Hugenholtz P.;
RT "A rank-normalized archaeal taxonomy based on genome phylogeny resolves
RT widespread incomplete and uneven classifications.";
RL bioRxiv 0:0-0(2020).
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DR EMBL; Y10251; CAA71297.1; -; Genomic_DNA.
DR EMBL; DUJS01000004; HII70853.1; -; Genomic_DNA.
DR AlphaFoldDB; P94950; -.
DR OMA; DMEPITP; -.
DR Proteomes; UP000619545; Unassembled WGS sequence.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd01483; E1_enzyme_family; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR InterPro; IPR012028; UCP006529_dinclt.
DR Pfam; PF00899; ThiF; 1.
DR PIRSF; PIRSF006529; UCP006529_dinclt; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE 4: Predicted;
FT DOMAIN 12..115
FT /note="THIF-type NAD/FAD binding fold"
FT /evidence="ECO:0000259|Pfam:PF00899"
SQ SEQUENCE 224 AA; 24753 MW; 1D31720FE402C7F2 CRC64;
MEPDELIEEL ELRKRPRGTV LLCGIGRLGF RVFLRLLETH RGGPKRIVCV DGQRVEPDDI
IHLRHGARIG ENKAEFAARL GRVHPLREVH AEPEFVTEEN ASELVDTWEP DVVVITIAGG
RTTPVTAALA REARRFGAVT VSTGGVFGYG SEEVRVVQLE EAEGPVAREL REYGAPSDHV
LVTTGRYIRD PDPIPPMVLE RVADELTELA LRALSNPSRG DDDS
//
