ID PHYA_PEA Reviewed; 1124 AA.
AC P15001;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1990, sequence version 1.
DT 24-JAN-2024, entry version 127.
DE RecName: Full=Phytochrome A;
GN Name=PHYA;
OS Pisum sativum (Garden pea) (Lathyrus oleraceus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Fabeae; Pisum.
OX NCBI_TaxID=3888;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Alaska;
RX AGRICOLA=IND92000014; DOI=10.1007/BF00017469;
RA Sato N.;
RT "Nucleotide sequence and expression of the phytochrome gene in Pisum
RT sativum: differential regulation by light of multiple transcripts.";
RL Plant Mol. Biol. 11:697-710(1988).
CC -!- FUNCTION: Regulatory photoreceptor which exists in two forms that are
CC reversibly interconvertible by light: the Pr form that absorbs
CC maximally in the red region of the spectrum and the Pfr form that
CC absorbs maximally in the far-red region. Photoconversion of Pr to Pfr
CC induces an array of morphogenic responses, whereas reconversion of Pfr
CC to Pr cancels the induction of those responses. Pfr controls the
CC expression of a number of nuclear genes including those encoding the
CC small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B
CC binding protein, protochlorophyllide reductase, rRNA, etc. It also
CC controls the expression of its own gene(s) in a negative feedback
CC fashion.
CC -!- SUBUNIT: Homodimer.
CC -!- PTM: Contains one covalently linked phytochromobilin chromophore.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the phytochrome family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; M37217; AAA33682.1; -; Genomic_DNA.
DR EMBL; X14077; CAA32242.1; -; Genomic_DNA.
DR PIR; S06856; S06856.
DR AlphaFoldDB; P15001; -.
DR SMR; P15001; -.
DR EnsemblPlants; Psat6g156640.1; Psat6g156640.1.cds; Psat6g156640.
DR Gramene; Psat6g156640.1; Psat6g156640.1.cds; Psat6g156640.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR GO; GO:0009585; P:red, far-red light phototransduction; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.270; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013654; PAS_2.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR016132; Phyto_chromo_attachment.
DR InterPro; IPR013516; Phyto_chromo_BS.
DR InterPro; IPR001294; Phytochrome.
DR InterPro; IPR012129; Phytochrome_A-E.
DR InterPro; IPR013515; Phytochrome_cen-reg.
DR InterPro; IPR043150; Phytochrome_PHY_sf.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR47876; OS08G0260000 PROTEIN; 1.
DR PANTHER; PTHR47876:SF3; PHYTOCHROME 1; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF08446; PAS_2; 1.
DR Pfam; PF00360; PHY; 1.
DR PIRSF; PIRSF000084; Phytochrome; 1.
DR PRINTS; PR01033; PHYTOCHROME.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS00245; PHYTOCHROME_1; 1.
DR PROSITE; PS50046; PHYTOCHROME_2; 1.
PE 3: Inferred from homology;
KW Chromophore; Photoreceptor protein; Receptor; Repeat; Sensory transduction;
KW Transcription; Transcription regulation.
FT CHAIN 1..1124
FT /note="Phytochrome A"
FT /id="PRO_0000171980"
FT DOMAIN 218..401
FT /note="GAF"
FT DOMAIN 617..687
FT /note="PAS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT DOMAIN 750..821
FT /note="PAS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT DOMAIN 901..1120
FT /note="Histidine kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 323
FT /ligand="phytochromobilin"
FT /ligand_id="ChEBI:CHEBI:189064"
FT /note="covalent"
FT /evidence="ECO:0000250"
SQ SEQUENCE 1124 AA; 124028 MW; D94AD89F6AAF72ED CRC64;
MSTTRPSQSS NNSGRSRNSA RIIAQTTVDA KLHATFEESG SSFDYSSSVR VSGSVDGDQQ
PRSNKVTTAY LNHIQRGKQI QPFGCLLALD EKTCKVVAYS ENAPEMLTMV SHAVPSVGDH
PALGIGTDIR TVFTAPSASA LQKALGFAEV SLLNPILVHC KTSGKPFYAI IHRVTGSLII
DFEPVKPYEV PMTAAGALQS YKLAAKAITR LQSLASGSME RLCDTMVQEV FELTGYDRVM
AYKFHEDDHG EVIAEIAKPG LEPYLGLHYP ATDIPQAARF LFMKNKVRMI VDCNAKHVKV
LQDEKLPFDL TLCGSTLRAP HSCHLQYMAN MDSIASLVMA VVVNDSDEDG DSADAVLPQK
KKRLWGLVVC HNTTPRFVPF PLRYACEFLA QVFAIHVNKE IELEYQILEK NILRTQTLLC
DMLMRDAPLG IVSQSPNIMD LVKCDGAALF YRNKLWLLGA TPTESQLREI ALWMSEYHTD
STGLSTDSLS DAGFPGALSL SDTVCGMAAV RITSKDIVFW FRSHTAAEIR WGGAKHEPGD
QDDGRKMHPR SSFKAFLEVV KARSVPWKDF EMDAIHSLQL ILRNASKDTD IIDLNTKAIN
TRLNDLKIEG MQELEAVTSE MVRLIETATV PILAVDVDGT VNGWNIKIAE LTGLPVGEAI
GKHLLTLVED SSTDIVKKML NLALQGEEEK NVQFEIKTHG DQVESGPISL IVNACASKDL
RENVVGVCFV AQDITAQKTV MDKFTRIEGD YKAIVQNPNQ LIPPIFGTDE FGWCCEWNAA
MIKLTGWKRE EVMDKMLLGE VFGTQMSCCR LKNQEAFVNF GIVLNKAMTG LETEKVPFGF
FSRKGKYVEC LLSVSKKIDA EGLVTGVFCF LQLASPELQQ ALHIQRLSEQ TALKRLKVLT
YMKRQIRNPL AGIVFSSKML EGTDLETEQK RIVNTSSQCQ RQLSKILDDS DLDGIIDGYL
DLEMAEFTLH EVLVTSLSQV MNRSNTKGIR IANDVAEHIA RETLYGDSLR LQQVLADFLL
ISINSTPNGG QVVIAASLTK EQLGKSVHLV NLELSITHGG SGVPEAALNQ MFGNNVLESE
EGISLHISRK LLKLMNGDVR YLKEAGKSSF ILSVELAAAH KLKG
//
