ID   PMBA_BUCBP              Reviewed;         448 AA.
AC   Q89AY6;
DT   29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   RecName: Full=Metalloprotease PmbA homolog;
DE            EC=3.4.-.-;
GN   Name=pmbA; OrderedLocusNames=bbp_083;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- FUNCTION: Probable metalloprotease. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase U62 family. {ECO:0000305}.
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DR   EMBL; AE016826; AAO26819.1; -; Genomic_DNA.
DR   RefSeq; WP_011091220.1; NC_004545.1.
DR   AlphaFoldDB; Q89AY6; -.
DR   SMR; Q89AY6; -.
DR   STRING; 224915.bbp_083; -.
DR   KEGG; bab:bbp_083; -.
DR   eggNOG; COG0312; Bacteria.
DR   HOGENOM; CLU_026425_0_0_6; -.
DR   OrthoDB; 9803618at2; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR   InterPro; IPR047657; PmbA.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR   PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR   Pfam; PF01523; PmbA_TldD_1st; 1.
DR   Pfam; PF19290; PmbA_TldD_2nd; 1.
DR   Pfam; PF19289; PmbA_TldD_3rd; 1.
DR   SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Metalloprotease; Protease; Reference proteome.
FT   CHAIN           1..448
FT                   /note="Metalloprotease PmbA homolog"
FT                   /id="PRO_0000142350"
SQ   SEQUENCE   448 AA;  49941 MW;  2F0BD672D4C21668 CRC64;
     MMKLSDITTQ ENDLKKIVEY ILNLAANHSV FSEVVIEKNC GVDVLIRKNS VNSIEFNKNN
     ILTITVYKNN RKGMVSSTDL SFKSIHNVFS SVMGIVFYSS PDEFSGLPDR KLLAINKVKD
     LDLYHDWDWN INHAIEIAKL SEREAFKEDK RIINSEGSCF NSLVRTRAFG NSLGMIECYS
     TTLYSTSCCV IAGDNGDMQR DFSFSVSRDM NDLNLPEKVG QDSAKKALSR LNSKKLLTMK
     TSAIFSSEIA FEFFINFAKA INGNNVYQKS TFLLHSLNTQ VFPNWLTIEE RPHIKKGLSS
     KCFDAEGVMT KTKKIVNKGI LKTWLLDTYS ARKINLVSTG NSGGIHNWLI LGNSNEGLQS
     LLKSMNTGLL ITELLGQGVS ITTGNYSRGA VGFWVDQGVI KYPVNEITIS GNLKNMFKDI
     VSIGNDIDKR HSIQSGSILL SQIQVSGI
//