ID PNO1_GIBZE Reviewed; 255 AA.
AC Q4IN63; A0A0E0RQD8; V6R455;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2005, sequence version 1.
DT 24-JAN-2024, entry version 92.
DE RecName: Full=Pre-rRNA-processing protein PNO1;
GN Name=PNO1; ORFNames=FGRRES_01345, FGSG_01345;
OS Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=229533;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=17823352; DOI=10.1126/science.1143708;
RA Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT "The Fusarium graminearum genome reveals a link between localized
RT polymorphism and pathogen specialization.";
RL Science 317:1400-1402(2007).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA Hammond-Kosack K.E.;
RT "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT graminearum.";
RL BMC Genomics 16:544-544(2015).
CC -!- FUNCTION: Required for small ribosomal subunit (SSU) synthesis. Has a
CC role in the processing of early nucleolar and late cytoplasmic pre-RNA
CC species (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the small ribosomal subunit, ribosomal RNA
CC processing complex (SSU RRP complex). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q99216}.
CC Nucleus, nucleolus {ECO:0000250|UniProtKB:Q99216}.
CC -!- SIMILARITY: Belongs to the PNO1 family. {ECO:0000305}.
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DR EMBL; DS231663; ESU06650.1; -; Genomic_DNA.
DR EMBL; HG970332; CEF73463.1; -; Genomic_DNA.
DR RefSeq; XP_011317135.1; XM_011318833.1.
DR AlphaFoldDB; Q4IN63; -.
DR SMR; Q4IN63; -.
DR STRING; 229533.Q4IN63; -.
DR GeneID; 23548788; -.
DR KEGG; fgr:FGSG_01345; -.
DR VEuPathDB; FungiDB:FGRAMPH1_01G03317; -.
DR eggNOG; KOG3273; Eukaryota.
DR HOGENOM; CLU_064992_0_2_1; -.
DR InParanoid; Q4IN63; -.
DR OrthoDB; 5473772at2759; -.
DR Proteomes; UP000070720; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR CDD; cd22391; KH-I_PNO1_rpt1; 1.
DR CDD; cd22392; KH-I_PNO1_rpt2; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF13; RNA-BINDING PROTEIN PNO1; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding.
FT CHAIN 1..255
FT /note="Pre-rRNA-processing protein PNO1"
FT /id="PRO_0000278371"
FT DOMAIN 179..228
FT /note="KH"
SQ SEQUENCE 255 AA; 28241 MW; 33D6DAD9DAEDF2C3 CRC64;
MPAPTALKQA ESAPLANDIS LPVEGADEEF LLDAPGAEDA DANVLVPVED SNDMQIDEEG
RPRFAPARDI DPVTRVETRK IPIPPHRMTP LKQSWTSIYP PLVEHLKLQC RMNIKRKTVE
LRSSKHTTES GALQKGEDFV KAFTLGFDVD DAIALLRLDD LYIQSFEIKD VRTMHGDSQA
RAIGRIAGKD GKTKFAIENA SRTRIVLADS KIHILGGFKN IHLARESVVS LILGKPPGKV
YGNLRTVAAR MKERF
//
