ID PV42B_ARATH Reviewed; 357 AA.
AC Q8GXI9; F4HS24; Q9SSD0;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 24-JAN-2024, entry version 91.
DE RecName: Full=SNF1-related protein kinase regulatory subunit gamma-like PV42b;
DE Short=AtPV42b;
DE AltName: Full=AKIN subunit gamma-like PV42b;
DE AltName: Full=CBS domain-containing protein CBSX4;
GN Name=PV42B; Synonyms=CBSX4; OrderedLocusNames=At1g80090;
GN ORFNames=F18B13.17, F18B13.42;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19400948; DOI=10.1186/1471-2164-10-200;
RA Kushwaha H.R., Singh A.K., Sopory S.K., Singla-Pareek S.L., Pareek A.;
RT "Genome wide expression analysis of CBS domain containing proteins in
RT Arabidopsis thaliana (L.) Heynh and Oryza sativa L. reveals their
RT developmental and stress regulation.";
RL BMC Genomics 10:200-200(2009).
RN [5]
RP FUNCTION, DISRUPTION PHENOTYPE, AND TISSUE SPECIFICITY.
RX PubMed=21533063; DOI=10.1371/journal.pone.0019033;
RA Fang L., Hou X., Lee L.Y., Liu L., Yan X., Yu H.;
RT "AtPV42a and AtPV42b redundantly regulate reproductive development in
RT Arabidopsis thaliana.";
RL PLoS ONE 6:E19033-E19033(2011).
CC -!- FUNCTION: Plays redundant role with PV42a in regulating male
CC gametogenesis and pollen tube guidance. {ECO:0000269|PubMed:21533063}.
CC -!- TISSUE SPECIFICITY: Expressed highly in rosette leaves, cauline leaves,
CC open flowers, developing siliques and dry seeds, but at a low level in
CC stems and floral buds. {ECO:0000269|PubMed:21533063}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype; probably due to a
CC complementation by PV42b. Shorter siliques and reduced seed sets in
CC pv42a and pv42b RNAi double mutant. {ECO:0000269|PubMed:21533063}.
CC -!- SIMILARITY: Belongs to the 5'-AMP-activated protein kinase gamma
CC subunit family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD55486.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC009322; AAD55486.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE36355.2; -; Genomic_DNA.
DR EMBL; AK118213; BAC42835.1; -; mRNA.
DR PIR; D96832; D96832.
DR RefSeq; NP_001319425.1; NM_001334956.1.
DR AlphaFoldDB; Q8GXI9; -.
DR SMR; Q8GXI9; -.
DR STRING; 3702.Q8GXI9; -.
DR PaxDb; 3702-AT1G80090-1; -.
DR ProteomicsDB; 236544; -.
DR EnsemblPlants; AT1G80090.1; AT1G80090.1; AT1G80090.
DR GeneID; 844349; -.
DR Gramene; AT1G80090.1; AT1G80090.1; AT1G80090.
DR KEGG; ath:AT1G80090; -.
DR Araport; AT1G80090; -.
DR TAIR; AT1G80090; CBSX4.
DR eggNOG; KOG1764; Eukaryota.
DR HOGENOM; CLU_062724_0_0_1; -.
DR InParanoid; Q8GXI9; -.
DR OMA; CIKPMAN; -.
DR OrthoDB; 671889at2759; -.
DR PhylomeDB; Q8GXI9; -.
DR PRO; PR:Q8GXI9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8GXI9; baseline and differential.
DR Genevisible; Q8GXI9; AT.
DR GO; GO:0009553; P:embryo sac development; IMP:UniProtKB.
DR GO; GO:0048443; P:stamen development; IMP:UniProtKB.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR PANTHER; PTHR13780; AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR13780:SF102; SNF1-RELATED PROTEIN KINASE REGULATORY SUBUNIT GAMMA-LIKE PV42B; 1.
DR Pfam; PF00571; CBS; 2.
DR SMART; SM00116; CBS; 3.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 3.
PE 2: Evidence at transcript level;
KW CBS domain; Reference proteome; Repeat.
FT CHAIN 1..357
FT /note="SNF1-related protein kinase regulatory subunit
FT gamma-like PV42b"
FT /id="PRO_0000403989"
FT DOMAIN 16..97
FT /note="CBS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 113..185
FT /note="CBS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 198..273
FT /note="CBS 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 293..351
FT /note="CBS 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ SEQUENCE 357 AA; 38525 MW; C60313644C993304 CRC64;
MQSYSRLMQF KVKDLMIDKR RLVEVPDNAT LGDALNTMVA NRVRAVPVAA KPGQWLGAGG
SMIVELDKQS GSARKQYIGM VTMLDVVAHI AGDDGESGLD KKMAAPVSSI IGHCPEGLSL
WSLNPNTSIM DCMEMLSKGI HRVLVPLDSN TENITGPELV ESASAYAMLS QMDLISFFFD
QSSQLHGILS HTVTDLSAIH NTVLALTSQA RVKDAIQCMS IAMLNAVPIV EASGEGEDHK
QLVDGKNRRV VGTFSASDLK GCHLATLRSW LPLNALEFVE KIPRTLLFTA ATSTPGRELV
TCHVTSTLAQ VIHMVTTKRV HRVWVVDQNG GLQGLVSLTD IIAVVRSALL SGAPDLF
//
