ID Q00G96_AEREN Unreviewed; 310 AA.
AC Q00G96;
DT 14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 14-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:ABG49400.1};
OS Aeromonas enteropelogenes (Aeromonas trota).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=29489 {ECO:0000313|EMBL:ABG49400.1};
RN [1] {ECO:0000313|EMBL:ABG49400.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MDC89 {ECO:0000313|EMBL:ABG49400.1};
RX PubMed=17012583; DOI=10.1099/ijs.0.64351-0;
RA Saavedra M.J., Figueras M.J., Martinez-Murcia A.J.;
RT "Updated phylogeny of the genus Aeromonas.";
RL Int. J. Syst. Evol. Microbiol. 56:2481-2487(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; DQ665875; ABG49400.1; -; Genomic_DNA.
DR AlphaFoldDB; Q00G96; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR InterPro; IPR018522; TopoIIA_CS.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS00177; TOPOISOMERASE_II; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 89..258
FT /note="DNA topoisomerase type IIA subunit B"
FT /evidence="ECO:0000259|Pfam:PF00204"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABG49400.1"
FT NON_TER 310
FT /evidence="ECO:0000313|EMBL:ABG49400.1"
SQ SEQUENCE 310 AA; 34425 MW; C785C954C87D1238 CRC64;
LTIRRNGHVY EQTYHLGEPQ APLKQIGDAT TTGTEVRFWP SPTIFSDTLF HYEILAKRLR
ELSFLNSGVS IRLMDERDGR EAHFCYEGGI KAFVEYLNQN KTPIHPKVFH FTTEQDGIGV
EVAMQWNDAY QEGVYCFTNN IPQRDGGTHL VGFRTALTRT LNSYMDKEDY SKKAKSAASG
DDVREGLIAV ISVKVPDPKF SSQTKDKLVS SEVKTAVEQA MGEKLADFLL ENPGDAKIVV
NKIIDAARAR EAARKARELT RRKGALDIAG LPGKLADCQE KDPALSELYI VEGDSAGGSA
KQGRNRKNQA
//
