ID   Q02A61_SOLUE            Unreviewed;       297 AA.
AC   Q02A61;
DT   14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   14-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Dihydrodipicolinate synthetase {ECO:0000313|EMBL:ABJ82065.1};
GN   OrderedLocusNames=Acid_1067 {ECO:0000313|EMBL:ABJ82065.1};
OS   Solibacter usitatus (strain Ellin6076).
OC   Bacteria; Acidobacteriota; Terriglobia; Bryobacterales; Solibacteraceae;
OC   Solibacter.
OX   NCBI_TaxID=234267 {ECO:0000313|EMBL:ABJ82065.1};
RN   [1] {ECO:0000313|EMBL:ABJ82065.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Ellin6076 {ECO:0000313|EMBL:ABJ82065.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Janssen P.H., Kuske C.R., Richardson P.;
RT   "Complete sequence of Solibacter usitatus Ellin6076.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
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DR   EMBL; CP000473; ABJ82065.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q02A61; -.
DR   STRING; 234267.Acid_1067; -.
DR   KEGG; sus:Acid_1067; -.
DR   eggNOG; COG0329; Bacteria.
DR   HOGENOM; CLU_049343_0_1_0; -.
DR   InParanoid; Q02A61; -.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128:SF72; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365}.
FT   ACT_SITE        140
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   ACT_SITE        168
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   BINDING         49
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
FT   BINDING         210
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ   SEQUENCE   297 AA;  32524 MW;  F16754D17198213C CRC64;
     MAPMKLQGIF PPITTPFDHK GDIYLSKIQH NVEKWNLTTL SGYVVMGSTG ESVMVTPEEK
     YTVWELVAKH AAAEKLLIAG TGVESVRETV DLTNRAAAIG YRAAMVRTPH YYKNLINRTD
     AQILYFRAVA DRAKIPLIIY NWPQTTGIDI SVEAVNALSG HPNIIAIKES SGNLEKVMQM
     IREVEPGFQV LVGSAPTLWP SLLMGACGAI LAYANAAPYS VIAIWEAYRT REEAAGLDWQ
     SRIARAAALV TTKYGIPGLK HAMDLNGYYG GPPRLPLTVP SPAAKQEIEQ AFRDLKG
//