ID Q08MU2_STIAD Unreviewed; 720 AA.
AC Q08MU2;
DT 31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Adenylate cyclase {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=STIAU_8296 {ECO:0000313|EMBL:EAU61800.1};
OS Stigmatella aurantiaca (strain DW4/3-1).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Archangiaceae; Stigmatella.
OX NCBI_TaxID=378806 {ECO:0000313|EMBL:EAU61800.1, ECO:0000313|Proteomes:UP000032702};
RN [1] {ECO:0000313|EMBL:EAU61800.1, ECO:0000313|Proteomes:UP000032702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DW4/3-1 {ECO:0000313|EMBL:EAU61800.1,
RC ECO:0000313|Proteomes:UP000032702};
RA Nierman W.C.;
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC {ECO:0000256|ARBA:ARBA00005381}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAU61800.1}.
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DR EMBL; AAMD01000327; EAU61800.1; -; Genomic_DNA.
DR AlphaFoldDB; Q08MU2; -.
DR PATRIC; fig|378806.16.peg.534; -.
DR Proteomes; UP000032702; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 242..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 443..495
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 533..664
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REGION 18..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAU61800.1"
SQ SEQUENCE 720 AA; 76816 MW; 6A4DF065E2181CEA CRC64;
GCALSALRAR GAGAALRWAG AGAVPGAAHR RGPRRRGDGG QQARRGRHLP CPPAPRGPGS
RQQPRLTRAL RLKASPRRPA APGGPPGRGA APARASPRPR PRARGWPPSP SGLALNGLVQ
APVHLGHASA AQLSEHAIGA DLPVTNGVLV RLVLLKVSHG PHGSGLCPDR RQVSRVLLAC
SRSKQAQPVS PGHRVSPPLV DTAQARRRKI LPLERTAEHP ALTGCAPMTP PSDVRLSVGL
RLLLHSGSVL VGLFTFVYAR LVCTFICGLP TPVLARTVAI LTVLHISLRE LLLQRVPLSG
KSASPARRAW LLSVLSWGVT GLAASLLHKA QYPAFPLFSH VKFAMGYGLL GGALLGQVEY
LLFERALPPA PSVSRAEQLR ERLGRRLIEG YVIFTTVPAA VLLLTLLRFI WELHGESHYV
VEAAMMSLGF TGIALGAAVA YGRSVRRDTE RLLEAVRRVG SGDFQPGAST SRPDELFLVA
EGINEMAGGL QLRERIREAF GRFVSPQVAS EFIEKYARHG KTAVMGGERK DVVVLFSDLR
DFTHLSESLA PEVLIEVLNG YFQEMVGAIQ QHGGMVDKFI GDAVLAVFGL TEGEANPARA
AVAAGLEMQR RLEAYNARLA ERGIQLRSGV GIHAGEAVAG YLGSTDRMEF TVIGHTVNVA
SRIEGQAREP RPPLLFSEEV ARRFGDAFGV KDVGSVPLKG VAHEVRLLTV TGEGGSIQAA
//
