ID Q0BXT6_HYPNA Unreviewed; 547 AA.
AC Q0BXT6;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Putative penicillin-binding protein 2 {ECO:0000313|EMBL:ABI76637.1};
GN OrderedLocusNames=HNE_3030 {ECO:0000313|EMBL:ABI76637.1};
OS Hyphomonas neptunium (strain ATCC 15444).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomonadales;
OC Hyphomonadaceae; Hyphomonas.
OX NCBI_TaxID=228405 {ECO:0000313|EMBL:ABI76637.1, ECO:0000313|Proteomes:UP000001959};
RN [1] {ECO:0000313|EMBL:ABI76637.1, ECO:0000313|Proteomes:UP000001959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15444 {ECO:0000313|EMBL:ABI76637.1,
RC ECO:0000313|Proteomes:UP000001959};
RX PubMed=16980487; DOI=10.1128/JB.00111-06;
RA Badger J.H., Hoover T.R., Brun Y.V., Weiner R.M., Laub M.T., Alexandre G.,
RA Mrazek J., Ren Q., Paulsen I.T., Nelson K.E., Khouri H.M., Radune D.,
RA Sosa J., Dodson R.J., Sullivan S.A., Rosovitz M.J., Madupu R.,
RA Brinkac L.M., Durkin A.S., Daugherty S.C., Kothari S.P., Giglio M.G.,
RA Zhou L., Haft D.H., Selengut J.D., Davidsen T.M., Yang Q., Zafar N.,
RA Ward N.L.;
RT "Comparative genomic evidence for a close relationship between the
RT dimorphic prosthecate bacteria Hyphomonas neptunium and Caulobacter
RT crescentus.";
RL J. Bacteriol. 188:6841-6850(2006).
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DR EMBL; CP000158; ABI76637.1; -; Genomic_DNA.
DR RefSeq; WP_011648004.1; NC_008358.1.
DR AlphaFoldDB; Q0BXT6; -.
DR STRING; 228405.HNE_3030; -.
DR KEGG; hne:HNE_3030; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_2_5; -.
DR Proteomes; UP000001959; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001959};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 50..159
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 210..514
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 528..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 58192 MW; F84A13F0FADDDF00 CRC64;
MSEASRDRTR LVGLAIGLLF VLMAGRGGFL ALSDAPSNAA VYPVAASLET RADIVDRHGE
LLATSVVSWS LWANPSLIWD GADAARQLAG VLPDLSEADL GARLSDPDRK FVWVKRGLTP
RQREHVVALG LEGLDFREEA RRAYPRGVLA GQVLGFTNVD GKGIAGIELA HDEALQGGGD
PVRLTLDIGA QAALEAELAT AAMDYDMKGG AAILMDTRSG EIRGMASWPP FDPNRASDTP
ADDPARTNRA ISAVYELGSI FKPFTIAAAL EVGAITPEDR FQVGQPLLIQ GRRISDTHWF
ARDANVWKIL SESSNIGTVQ VNYALGTQRQ QQFLERAGLT RRAPIDLPGS AAPLMPERFD
EVTAATVSYG HGISVTPLAF LLAFSAFGND GLMIAPVLVE AGADAGDIAA PAPVRLFSEE
TTHLVTQMMR DTVLQGTARR ADVAGYRVAG KTGTAEKPIA GGYAKDRNVS SFAAVFPADS
PQYALIVTLD EPKAIEDGTM TAAVNAAPVA GRIIERVAPL LEVDPRFEDL RPATAPPQAL
SQNRSEL
//
