ID Q0C644_HYPNA Unreviewed; 273 AA.
AC Q0C644;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Enoyl-CoA hydratase/isomerase family protein {ECO:0000313|EMBL:ABI76821.1};
GN OrderedLocusNames=HNE_0065 {ECO:0000313|EMBL:ABI76821.1};
OS Hyphomonas neptunium (strain ATCC 15444).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomonadales;
OC Hyphomonadaceae; Hyphomonas.
OX NCBI_TaxID=228405 {ECO:0000313|EMBL:ABI76821.1, ECO:0000313|Proteomes:UP000001959};
RN [1] {ECO:0000313|EMBL:ABI76821.1, ECO:0000313|Proteomes:UP000001959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15444 {ECO:0000313|EMBL:ABI76821.1,
RC ECO:0000313|Proteomes:UP000001959};
RX PubMed=16980487; DOI=10.1128/JB.00111-06;
RA Badger J.H., Hoover T.R., Brun Y.V., Weiner R.M., Laub M.T., Alexandre G.,
RA Mrazek J., Ren Q., Paulsen I.T., Nelson K.E., Khouri H.M., Radune D.,
RA Sosa J., Dodson R.J., Sullivan S.A., Rosovitz M.J., Madupu R.,
RA Brinkac L.M., Durkin A.S., Daugherty S.C., Kothari S.P., Giglio M.G.,
RA Zhou L., Haft D.H., Selengut J.D., Davidsen T.M., Yang Q., Zafar N.,
RA Ward N.L.;
RT "Comparative genomic evidence for a close relationship between the
RT dimorphic prosthecate bacteria Hyphomonas neptunium and Caulobacter
RT crescentus.";
RL J. Bacteriol. 188:6841-6850(2006).
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; CP000158; ABI76821.1; -; Genomic_DNA.
DR RefSeq; WP_011645099.1; NC_008358.1.
DR AlphaFoldDB; Q0C644; -.
DR STRING; 228405.HNE_0065; -.
DR KEGG; hne:HNE_0065; -.
DR eggNOG; COG1024; Bacteria.
DR HOGENOM; CLU_009834_7_0_5; -.
DR UniPathway; UPA00659; -.
DR Proteomes; UP000001959; Chromosome.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045002; Ech1-like.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR PANTHER; PTHR43149:SF1; DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43149; ENOYL-COA HYDRATASE; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 3: Inferred from homology;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ABI76821.1};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000001959}.
FT REGION 73..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 273 AA; 29750 MW; 044A975C21E4D4A9 CRC64;
MNDRVLITML EDGIADVRLN RTDKMNALDP AMFAGIAEAI DKLKAMKGLR VVVLSGEGRA
FCAGLDLSNF TGGGGGSGEK KPEKASPTSN LDGRSHGIAN LAQYVAWGWR ELNVPVIAAA
HGVAFGGGFQ ILSGADIRFI HPETRCAIME MKWGLVPDMA GYPLWRGNVR DDVLRELTYT
NREFRGTEAQ ALGFATHVSE NPLEDALALA RVMAAKHPAA MQGAKRLFNA MQDATDAELL
QMESDEQNKV MRTPNQMEAV MSEMQKRKPV FAE
//
