ID Q0H2D5_BREVE Unreviewed; 298 AA.
AC Q0H2D5;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0000313|EMBL:ABC50110.1};
GN Name=crtE {ECO:0000313|EMBL:ABC50110.1};
OS Brevundimonas vesicularis (Pseudomonas vesicularis).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Brevundimonas.
OX NCBI_TaxID=41276 {ECO:0000313|EMBL:ABC50110.1};
RN [1] {ECO:0000313|EMBL:ABC50110.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DC263 {ECO:0000313|EMBL:ABC50110.1};
RX PubMed=16781830; DOI=10.1016/j.gene.2006.04.017;
RA Tao L., Rouviere P.E., Cheng Q.;
RT "A carotenoid synthesis gene cluster from a non-marine Brevundimonas that
RT synthesizes hydroxylated astaxanthin.";
RL Gene 379:101-108(2006).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DQ309446; ABC50110.1; -; Genomic_DNA.
DR AlphaFoldDB; Q0H2D5; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 298 AA; 31477 MW; F67461EC86D2A53A CRC64;
MAIVGIRRQT PLVGASCAPD DLRLQVQARL AEVAPAHDGL LSTAAREALL GRGKRVRPVL
AMLAAAHVGG DPEDALEYAC ALEMVHAASL VLDDLPCMDD ASLRRGQPTL HHRHGEDTAV
LAAVALLNQA TRLVLQTAAP AETRLAALDL LTQAIGFDGL SEGQMRDLRD DARDRDESAL
RQINDLKTGA LFVATVRGGG LLGGGDAQDL ARLSIFGEAI GFAFQLCDDL LDVCSTVDAA
GKDVGQDDDT TTFVDLWGEC RTRAAVRQSL GKAVEAVGHD SPLAVYVLDL FQQAELGV
//
