ID Q0JWK0_STRAM Unreviewed; 197 AA.
AC Q0JWK0;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=nicotinamidase {ECO:0000256|ARBA:ARBA00039017};
DE EC=3.5.1.19 {ECO:0000256|ARBA:ARBA00039017};
DE AltName: Full=Nicotinamide deamidase {ECO:0000256|ARBA:ARBA00043224};
GN ORFNames=DSMT0084 {ECO:0000313|EMBL:CAK51165.1};
OS Streptomyces ambofaciens.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1889 {ECO:0000313|EMBL:CAK51165.1};
RN [1] {ECO:0000313|EMBL:CAK51165.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM40697 {ECO:0000313|EMBL:CAK51165.1};
RX PubMed=16952952; DOI=10.1128/JB.00734-06;
RA Choulet F., Gallois A., Aigle B., Mangenot S., Gerbaud C., Truong C.,
RA Francou F.X., Borges F., Fourrier C., Guerineau M., Decaris B., Barbe V.,
RA Pernodet J.L., Leblond P.;
RT "Intraspecific variability of the terminal inverted repeats of the linear
RT chromosome of Streptomyces ambofaciens.";
RL J. Bacteriol. 188:6599-6610(2006).
CC -!- PATHWAY: Cofactor biosynthesis; nicotinate biosynthesis; nicotinate
CC from nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00037900}.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR EMBL; AM279694; CAK50927.1; -; Genomic_DNA.
DR EMBL; AM279695; CAK51165.1; -; Genomic_DNA.
DR RefSeq; WP_063480834.1; NZ_CP012949.1.
DR AlphaFoldDB; Q0JWK0; -.
DR PATRIC; fig|1889.10.peg.7325; -.
DR OrthoDB; 9791276at2; -.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR11080:SF2; LD05707P; 1.
DR PANTHER; PTHR11080; PYRAZINAMIDASE/NICOTINAMIDASE; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642}.
FT DOMAIN 5..190
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
SQ SEQUENCE 197 AA; 20613 MW; B9EA996748A5CD6C CRC64;
MSRGLIVVDV QNDFCEGGSV PVAGGARIAT AVAALVERSA GTDYQYIVAT RDHHIDPGSH
FSENPDFKDS FPVHCVVGGE GGEFHPNFAP AATGGKVDAV FFKGAHSASK SGFEGFDEHG
TPLAEWLRSR AVEDVDVVGI ATDHCVRATA LDAVKAGFRA RVLLDYSVGV APDTTASTLE
DFRRAGVAVS GETPVPQ
//
