ID   Q0K455_CUPNH            Unreviewed;       473 AA.
AC   Q0K455;
DT   03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2006, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=Aldehyde dehydrogenase, NAD(P)-dependent {ECO:0000313|EMBL:CAJ95219.1};
DE            EC=1.2.1.3 {ECO:0000313|EMBL:CAJ95219.1};
GN   OrderedLocusNames=H16_B0421 {ECO:0000313|EMBL:CAJ95219.1};
OS   Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS   / H16 / Stanier 337) (Ralstonia eutropha).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ95219.1, ECO:0000313|Proteomes:UP000008210};
RN   [1] {ECO:0000313|EMBL:CAJ95219.1, ECO:0000313|Proteomes:UP000008210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC   337 {ECO:0000313|Proteomes:UP000008210};
RX   PubMed=16964242; DOI=10.1038/nbt1244;
RA   Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA   Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA   Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT   "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT   eutropha H16.";
RL   Nat. Biotechnol. 24:1257-1262(2006).
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DR   EMBL; AM260480; CAJ95219.1; -; Genomic_DNA.
DR   RefSeq; WP_011616580.1; NZ_CP039288.1.
DR   AlphaFoldDB; Q0K455; -.
DR   STRING; 381666.H16_B0421; -.
DR   GeneID; 57646305; -.
DR   KEGG; reh:H16_B0421; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_0_0_4; -.
DR   OrthoDB; 6187633at2; -.
DR   Proteomes; UP000008210; Chromosome 2.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07138; ALDH_CddD_SSP0762; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR42804; ALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR42804:SF1; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:CAJ95219.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008210}.
FT   DOMAIN          13..471
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
SQ   SEQUENCE   473 AA;  49373 MW;  1EFE10D9245AF94A CRC64;
     METLEKFYIA GGWVAPSPGS TLAEIVNPAS EAVIGTLAMG TAADVDRAVA AARAAFPAWS
     ESGREDRIAL LERIITRYQE RLDDMARAVR LEMGAPATLA RNVHAMAGLG QLHATLAALR
     TFEFETARGK GVIRREAIGV AALVTPWNWP LNQIVAKVAP AIAAGCAVVL KPSEIAPLDA
     RIFAEIMHDA GTPPGVFNML SGTGQTVGTA LSSHPDVDVV SFTGSTRAGI QVAINAAPTV
     KRVAQELGGK SALVILDDAD LRAAVSGGVA QCMANSGQTC VAPTRMLVPR ERYDEAVGIA
     AALADATNVG DPEDPATSMG PLSSRAQYER VQHLIAVGMG EGARVAAGGL GRPRGLERGF
     FARPTIFAGV RNDMAIAREE IFGPVLVMIA HDGDDHAVAL ANDSPFGLAG YVMSGNADRA
     RKVARRLRAG MVRINGAPPD LSLPFGGYKQ SGNGREFGPE GIAEFLETKS IIG
//