ID Q0K4R8_CUPNH Unreviewed; 308 AA.
AC Q0K4R8;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Transcriptional regulator, LysR-family {ECO:0000313|EMBL:CAJ95006.1};
GN OrderedLocusNames=H16_B0205 {ECO:0000313|EMBL:CAJ95006.1};
OS Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS / H16 / Stanier 337) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ95006.1, ECO:0000313|Proteomes:UP000008210};
RN [1] {ECO:0000313|EMBL:CAJ95006.1, ECO:0000313|Proteomes:UP000008210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC 337 {ECO:0000313|Proteomes:UP000008210};
RX PubMed=16964242; DOI=10.1038/nbt1244;
RA Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT eutropha H16.";
RL Nat. Biotechnol. 24:1257-1262(2006).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM260480; CAJ95006.1; -; Genomic_DNA.
DR RefSeq; WP_011616412.1; NZ_CP039288.1.
DR AlphaFoldDB; Q0K4R8; -.
DR STRING; 381666.H16_B0205; -.
DR GeneID; 57646084; -.
DR KEGG; reh:H16_B0205; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_5_4; -.
DR OrthoDB; 8587114at2; -.
DR Proteomes; UP000008210; Chromosome 2.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30293:SF0; NITROGEN ASSIMILATION REGULATORY PROTEIN NAC; 1.
DR PANTHER; PTHR30293; TRANSCRIPTIONAL REGULATORY PROTEIN NAC-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000008210};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 308 AA; 32848 MW; 745CE777FA4124BF CRC64;
MELRQLRYFV SVIEHGSMGK AALELGVVTS ALSQQISRLE SELSTRLLQR TSTGVVATDA
GLAFWRQAQL ALRHIDDAAL AARQARLSGH VSVGLPPSTA AVLALPFMQA MRERYPDVRL
RMVESLSGYL GTMLSARQID LAVLFSEEPA QRWSVLPLLD ERLFVIGAEG LAGMPRGEQT
SVAALGKLPL ILPSGSHGLR ALVAACFRQA KREPQVVAEI DGLAILMDAV RGGLGATIQP
GAALARSHGT PYRSILVTDA GATRPNLLVS LSDDELSPAG LAARVVLADV ATTLVREGRW
PGATLRPR
//
