ID Q0K873_CUPNH Unreviewed; 259 AA.
AC Q0K873;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Transcriptional regulator, IclR-family {ECO:0000313|EMBL:CAJ93798.1};
GN OrderedLocusNames=H16_A2719 {ECO:0000313|EMBL:CAJ93798.1};
OS Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS / H16 / Stanier 337) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ93798.1, ECO:0000313|Proteomes:UP000008210};
RN [1] {ECO:0000313|EMBL:CAJ93798.1, ECO:0000313|Proteomes:UP000008210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC 337 {ECO:0000313|Proteomes:UP000008210};
RX PubMed=16964242; DOI=10.1038/nbt1244;
RA Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT eutropha H16.";
RL Nat. Biotechnol. 24:1257-1262(2006).
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DR EMBL; AM260479; CAJ93798.1; -; Genomic_DNA.
DR RefSeq; WP_011615795.1; NZ_CP039287.1.
DR AlphaFoldDB; Q0K873; -.
DR STRING; 381666.H16_A2719; -.
DR GeneID; 57644842; -.
DR KEGG; reh:H16_A2719; -.
DR PATRIC; fig|381666.6.peg.3110; -.
DR eggNOG; COG1414; Bacteria.
DR HOGENOM; CLU_062618_0_1_4; -.
DR OrthoDB; 8960000at2; -.
DR Proteomes; UP000008210; Chromosome 1.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF34; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008210};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..73
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 74..258
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 259 AA; 28080 MW; D6AF7BD4E5251F56 CRC64;
MPQAEAAKKD ELLESLSKGL ALLRLFAGGA ERLTMQDVAE QLDVTRAAAR RLLLTLEHNG
YVAQDGRHFA LTPRVIELGY AYFASMSLPQ VARPYLQGLC ESLGESCSVG VLDAESVVLV
AREEPRQLLR VDMALGRRMP AYAHSLGRVL LAGLDDDALE AYLAGATLRK LTPFTVSSRT
ALARTLRQVR TDGYCVLVSE LVDGYAGISV PLRDQAGKPV AGLGFSMVLG SRDQAQLETR
FLGPLREAAA RIETILQAR
//
