ID Q0MVS8_9EURO Unreviewed; 1007 AA.
AC Q0MVS8;
DT 19-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 19-SEP-2006, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
DE Flags: Fragment;
GN Name=RPB1 {ECO:0000313|EMBL:ABH09098.1};
OS Pyrenula reebiae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Pyrenulales; Pyrenulaceae; Pyrenula.
OX NCBI_TaxID=1776377 {ECO:0000313|EMBL:ABH09098.1};
RN [1] {ECO:0000313|EMBL:ABH09098.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AFTOL-ID 387 {ECO:0000313|EMBL:ABH09098.1};
RX PubMed=17051209; DOI=10.1038/nature05110;
RA James T.Y., Kauff F., Schoch C.L., Matheny P.B., Hofstetter V., Cox C.J.,
RA Celio G., Gueidan C., Fraker E., Miadlikowska J., Lumbsch H.T., Rauhut A.,
RA Reeb V., Arnold A.E., Amtoft A., Stajich J.E., Hosaka K., Sung G.H.,
RA Johnson D., O'Rourke B., Crockett M., Binder M., Curtis J.M., Slot J.C.,
RA Wang Z., Wilson A.W., Schussler A., Longcore J.E., O'Donnell K.,
RA Mozley-Standridge S., Porter D., Letcher P.M., Powell M.J., Taylor J.W.,
RA White M.M., Griffith G.W., Davies D.R., Humber R.A., Morton J.B.,
RA Sugiyama J., Rossman A.Y., Rogers J.D., Pfister D.H., Hewitt D., Hansen K.,
RA Hambleton S., Shoemaker R.A., Kohlmeyer J., Volkmann-Kohlmeyer B.,
RA Spotts R.A., Serdani M., Crous P.W., Hughes K.W., Matsuura K., Langer E.,
RA Langer G., Untereiner W.A., Lucking R., Budel B., Geiser D.M., Aptroot A.,
RA Diederich P., Schmitt I., Schultz M., Yahr R., Hibbett D.S., Lutzoni F.,
RA McLaughlin D.J., Spatafora J.W., Vilgalys R.;
RT "Reconstructing the early evolution of Fungi using a six-gene phylogeny.";
RL Nature 443:818-822(2006).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|ARBA:ARBA00006460, ECO:0000256|RuleBase:RU004279}.
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DR EMBL; DQ840558; ABH09098.1; -; Genomic_DNA.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd02733; RNAP_II_RPB1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 159..467
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT REGION 71..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 613..640
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 71..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABH09098.1"
FT NON_TER 1007
FT /evidence="ECO:0000313|EMBL:ABH09098.1"
SQ SEQUENCE 1007 AA; 113173 MW; 556E7D3A9E23472A CRC64;
HIELAVPVYH HGFLKMVKKI LETVCHNCGK VKAIDVSGEE LRLAKAIPNK RTRFEKVWQL
SKKHRICEAD ISEEGDQEFS KEKGPPRPKH GGCGNAQPEI RLSGLNLMTS WKPTKDGDNE
PVQAETRPLT PPTALNILRL MNDEEMEEIG LDTKNARPEW MILSVLPVPP PPVRPSISMD
GSGQGARGED DLTFKLGDIV RANQNVRRVQ QEGSPEHILN EHVQLLQWHV ATYMNNDIAG
MDGLKAQHKT GRPIKSIRAR LKGKDGRLRQ NLMGKRVDFS ARTVITGDPN LSLDEVGVPR
SIARNLTYPE VVTPFNVDKL KRLVANGPTE HPGARFVVRD DGTRIDLRHH KRTSELTLQF
GWKVERHISH GDIILFNRQP SLXXXXXXXX RVRVMPYSTF RLNLSVTTPY NADFDGDEMN
LHVPQSEEAR AELANLCMVP LNIVSPQRNG PLMGIVQDTL CGIYKICRRD VFLSREQVMN
TMLWVPDWDG VIPQPAVLKP RPRWTGKQVI SMVLPPNLNL VRIDKDSGEE YERFSPLADG
GLFVDRGELM FGLFNKKSVG TSAGGIIHTV FNEFGPETAM AFFNGAQTVV NYWLLHYGFS
IGIGDTVPDN ATVESIKEQV NQRKSEVESI TQKAQNQELE AQPGMNVRET FESKVAKALN
DARDGAGGAT ESSLKDLNNA IQMARAGSKG STINIAQMTA IVGQQSVEGK RIPFGFKYRT
LPHFAKDDYS AQSRGFVENS YLRGLTPSEF FFHAMAGREG LIDTAVKTAE TGYIQRRLVK
ALEETTVRYD NTVRDARGNV VQFIYGEDGL DGAHIENQRV DVITMSDEAF NKRYRVDLME
KAPQFPKGRL ETDFRADVER QQLLDEEYDQ LREDRAFLRS FRKGSDEMMQ LPLNILRIID
QAKTTFKVDA TQTCNLDPKH VIPEVQRLLR ELVVVRGDDT ISDEAQTNAT LLFKAQLRSR
LAFKRLVNEN RLSTVAFNHV IGNVKSRWVK AQAQPGEMVG VLAAQSI
//
