ID   Q0NPW6_COWPX            Unreviewed;       785 AA.
AC   Q0NPW6;
DT   19-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   19-SEP-2006, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=Uncoating factor OPG117 {ECO:0000256|ARBA:ARBA00034867};
GN   ORFNames=CPXV_GER91_3_114 {ECO:0000313|EMBL:ABD97461.1};
OS   Cowpox virus (CPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=10243 {ECO:0000313|EMBL:ABD97461.1, ECO:0000313|Proteomes:UP000136830};
OH   NCBI_TaxID=10129; Apodemus sylvaticus (European woodmouse).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9785; Loxodonta africana (African elephant).
OH   NCBI_TaxID=29092; Microtus agrestis (Short-tailed field vole).
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
OH   NCBI_TaxID=447135; Myodes glareolus (Bank vole) (Clethrionomys glareolus).
RN   [1] {ECO:0000313|EMBL:ABD97461.1, ECO:0000313|Proteomes:UP000136830}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Germany 91-3 {ECO:0000313|EMBL:ABD97461.1};
RX   PubMed=16873609; DOI=10.1126/science.1125134;
RA   Esposito J.J., Sammons S.A., Frace A.M., Osborne J.D., Olsen-Rasmussen M.,
RA   Zhang M., Govil D., Damon I.K., Kline R., Laker M., Li Y., Smith G.L.,
RA   Meyer H., LeDuc J.W., Wohlhueter R.M.;
RT   "Genome sequence diversity and clues to the evolution of variola (smallpox)
RT   virus.";
RL   Science 313:807-812(2006).
CC   -!- SIMILARITY: Belongs to the orthopoxvirus OPG117 family.
CC       {ECO:0000256|ARBA:ARBA00034752}.
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DR   EMBL; DQ437593; ABD97461.1; -; Genomic_DNA.
DR   Proteomes; UP000136830; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR004968; DNA_primase/NTPase_C.
DR   InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR   Pfam; PF08706; D5_N; 1.
DR   Pfam; PF03288; Pox_D5; 1.
DR   PROSITE; PS51206; SF3_HELICASE_1; 1.
PE   3: Inferred from homology;
FT   DOMAIN          477..639
FT                   /note="SF3 helicase"
FT                   /evidence="ECO:0000259|PROSITE:PS51206"
SQ   SEQUENCE   785 AA;  90470 MW;  18C58C84C36C43BB CRC64;
     MDVTIRGNDI IFVLKTIGVP SACRQNEDPR FVEAFKCDEL ERYIENNPEC TLFESLRDEE
     AYSIVRIFMD VDLDACLDEI DYLTAIQDFI IEVSNCVARF AFIECGAIHE NVIKSMRSNF
     SLTKSTNRDK TSFHIIFLDT YTTMDTLIAM KRTLLELSRS SENPLTRSID TAVYRRKTTL
     RVVGTRKNPN CDTIHVMQPP HDNIEDYLFT YVDMNNDSYY FSLQRRLEDL VPDKLWEPGF
     ISFEDAIKRV SKIFINSIIN FNDLDENNFT TVPLVIDYVT PCALCKKRSH KHPHQLSLEN
     GAIRIYKTGN PHSCKVKIVP LDGNKLFNIA QRILDTNSVL LTERGDHIVW INNSWKFNSE
     EPLITKLILS IRHQLPKEYS SELLCPRKRK TVEANIRDML VDSVETDTYP DKLPFKNGVL
     DLVDGMFYSG DDAKKYTCTV STGFKFDDTK FVEDSPEMEE LMNIINDIQP LTDENKKNRE
     LYEKTLSSCL CGATKGCLTF FFGETATGKS TTKRLLKSAI GDLFVETGQT ILTDVLDKGP
     NPFIANMHLK RSVFCSELPD FACSGSKKIR SDNIKKLTEP CVIGRPCFSN KINNRNHATI
     IIDTNYKPVF DRIDNALMRR IAVVRFRTHF SQPSGREAAE NNDAYDKVKL LDEGLDGKIQ
     NNRYRFAFLY LLVKWYKKYH IPIMKLYPTP EEIPDFAFYL KIGTLLVSSS VKHIPLMTDL
     SKKGYILYDN VVTLPLNTFQ QKISKYFNSR LFGHDIESFI NRHKKFANVS DEYLQYIFIE
     DISSP
//