ID Q0P6B2_MOUSE Unreviewed; 640 AA.
AC Q0P6B2;
DT 19-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 19-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Far upstream element (FUSE) binding protein 1 {ECO:0000313|EMBL:AAH23780.1};
GN Name=Fubp1 {ECO:0000313|EMBL:AAH23780.1, ECO:0000313|MGI:MGI:1196294};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH23780.1};
RN [1] {ECO:0000313|EMBL:AAH23780.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N {ECO:0000313|EMBL:AAH23780.1};
RC TISSUE=Mammary tumor. C3 {ECO:0000313|EMBL:AAH23780.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC023780; AAH23780.1; -; mRNA.
DR RefSeq; XP_006501737.1; XM_006501674.1.
DR AlphaFoldDB; Q0P6B2; -.
DR EPD; Q0P6B2; -.
DR PeptideAtlas; Q0P6B2; -.
DR UCSC; uc008rsx.1; mouse.
DR AGR; MGI:1196294; -.
DR MGI; MGI:1196294; Fubp1.
DR BioGRID-ORCS; 51886; 5 hits in 80 CRISPR screens.
DR ChiTaRS; Fubp1; mouse.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd22478; KH-I_FUBP1_rpt1; 1.
DR CDD; cd22481; KH-I_FUBP1_rpt2; 1.
DR CDD; cd22484; KH-I_FUBP1_rpt3; 1.
DR CDD; cd22487; KH-I_FUBP1_rpt4; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 4.
DR InterPro; IPR015096; FUBP_C.
DR InterPro; IPR048249; KH-I_FUBP1_dom1.
DR InterPro; IPR048250; KH-I_FUBP1_dom2.
DR InterPro; IPR048251; KH-I_FUBP1_dom3.
DR InterPro; IPR048252; KH-I_FUBP1_dom4.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288:SF99; FAR UPSTREAM ELEMENT-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR Pfam; PF09005; DUF1897; 2.
DR Pfam; PF00013; KH_1; 4.
DR SMART; SM00322; KH; 4.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 4.
DR PROSITE; PS50084; KH_TYPE_1; 4.
PE 2: Evidence at transcript level;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 95..165
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 180..252
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 270..340
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 371..444
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 40..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 545..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..501
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 640 AA; 67196 MW; E374D6DCF1ECE804 CRC64;
MADYSTVPPP SSGSAGGGGG GVVNDAFKDA LQRARQIAAK IGGDAGTSLN SNDYGYGGQK
RPLEDGDQPD AKKVPPQNDS FGAQLPPMHQ QQSRSVMTEE YKVPDGMVGF IIGRGGEQIS
RIQQESGCKI QIAPDSGGLP ERSCMLTGTP ESVQSAKRLL DQIVEKGRPA PGFHHGDGPG
NAVQEIMIPA SKAGLVIGKG GETIKQLQER AGVKMVMIQD GPQNTGADKP LRITGDPYKV
QQAKEMVLEL IRDQGGFREV RNEYGSRIGG NEGIDVPIPR FAVGIVIGRN GEMIKKIQND
AGVRIQFKPD DGTTPDRIAQ ITGPPDRCQH AAEIITDLLR SVQAGNPGGP GPGGRGRGRG
QGNWNMGPPG GLQEFNFIVP TGKTGLIIGK GGETIKSISQ QSGARIELQR SPPPNADPNM
KLFTIRGTPQ QIDYARQLIE EKIGGPVNPL GPPVPHGPHG VPGPHGPPGP PGPGTPMGPY
NPAPYNPGPP GPAPHGPPAP YAPQGWGNAY PHWQQQAPPD PAKAGADPNS AAWAAYYAHY
YQQQAQPPPA APAGAPATTQ TNGQGDQQAP APAGQVDYTK AWEEYYKKMG QAVPAPAGAP
PGGQPDYSAA WAEYYRQQAA YYAQTSPQGM PQHPPAPQGQ
//
