ID Q0P9B3_CAMJE Unreviewed; 343 AA.
AC Q0P9B3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Sialic acid synthase (N-acetylneuraminic acid synthetase) {ECO:0000313|EMBL:CAL35258.1};
DE EC=4.1.3.- {ECO:0000313|EMBL:CAL35258.1};
GN Name=neuB1 {ECO:0000313|EMBL:CAL35258.1};
GN OrderedLocusNames=Cj1141 {ECO:0000313|EMBL:CAL35258.1};
OS Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC
OS 11168).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Campylobacteraceae; Campylobacter.
OX NCBI_TaxID=192222 {ECO:0000313|EMBL:CAL35258.1, ECO:0000313|Proteomes:UP000000799};
RN [1] {ECO:0000313|EMBL:CAL35258.1, ECO:0000313|Proteomes:UP000000799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700819 / NCTC 11168 {ECO:0000313|Proteomes:UP000000799};
RX PubMed=10688204; DOI=10.1038/35001088;
RA Parkhill J., Wren B.W., Mungall K., Ketley J.M., Churcher C., Basham D.,
RA Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K.,
RA Karlyshev A., Moule S., Pallen M.J., Penn C.W., Quail M., Rajandream M.A.,
RA Rutherford K.M., VanVliet A., Whitehead S., Barrell B.G.;
RT "The genome sequence of the food-borne pathogen Campylobacter jejuni
RT reveals hypervariable sequences.";
RL Nature 403:665-668(2000).
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DR EMBL; AL111168; CAL35258.1; -; Genomic_DNA.
DR PIR; H81318; H81318.
DR RefSeq; WP_002858213.1; NZ_SZUC01000001.1.
DR RefSeq; YP_002344534.1; NC_002163.1.
DR AlphaFoldDB; Q0P9B3; -.
DR SMR; Q0P9B3; -.
DR STRING; 192222.Cj1141; -.
DR PaxDb; 192222-Cj1141; -.
DR EnsemblBacteria; CAL35258; CAL35258; Cj1141.
DR GeneID; 905432; -.
DR KEGG; cje:Cj1141; -.
DR PATRIC; fig|192222.6.peg.1123; -.
DR eggNOG; COG2089; Bacteria.
DR HOGENOM; CLU_040465_0_1_7; -.
DR OrthoDB; 9781701at2; -.
DR Proteomes; UP000000799; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR013974; SAF.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:CAL35258.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000799}.
FT DOMAIN 286..343
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 343 AA; 38482 MW; 882E8DD57AD2DEAF CRC64;
MQIKIDKLTI SQKNPLIIPE IGINHNGSLE IAKLMVDAAK RAGAKIIKHQ THIVEDEMSQ
EAKNVIPGNA NISIYEIMEQ CALNYKDELA LKEYVEKQGL VYLSTPFSRA AANRLEDMGV
SAYKIGSGEC NNYPLIKHIA QFKKPMIIST GMNSIESIKP TVKILRDYEI PFVLLHTTNL
YPTPSHLVRL QAMLELYKEF NCLYGLSDHT TNNLACIGAI ALGASVLERH FTDTMDRKGP
DIVCSMDEST LKDLINQTQE MVLLRGDNNK NPLKEEQVTI DFAFASVVSI KDIKKGEILS
MDNIWVKRPS KGGISAKDFE AILGKRAKKD IKNNIQLTWD DFE
//
