ID Q0S5S7_RHOJR Unreviewed; 552 AA.
AC Q0S5S7;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=CoA ligase {ECO:0000313|EMBL:ABG97109.1};
DE EC=6.2.1.- {ECO:0000313|EMBL:ABG97109.1};
GN OrderedLocusNames=RHA1_ro05328 {ECO:0000313|EMBL:ABG97109.1};
OS Rhodococcus jostii (strain RHA1).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=101510 {ECO:0000313|EMBL:ABG97109.1, ECO:0000313|Proteomes:UP000008710};
RN [1] {ECO:0000313|Proteomes:UP000008710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RHA1 {ECO:0000313|Proteomes:UP000008710};
RX PubMed=17030794; DOI=10.1073/pnas.0607048103;
RA McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C.,
RA Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H.,
RA Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H.,
RA Smailus D., Siddiqui A.S., Marra M.A., Jones S.J.M., Holt R.,
RA Brinkman F.S.L., Miyauchi K., Fukuda M., Davies J.E., Mohn W.W.,
RA Eltis L.D.;
RT "The complete genome of Rhodococcus sp. RHA1 provides insights into a
RT catabolic powerhouse.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006).
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DR EMBL; CP000431; ABG97109.1; -; Genomic_DNA.
DR AlphaFoldDB; Q0S5S7; -.
DR KEGG; rha:RHA1_ro05328; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_2_11; -.
DR Proteomes; UP000008710; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ABG97109.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008710}.
FT DOMAIN 52..412
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 463..538
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 552 AA; 58312 MW; 6C02577E63AAEC56 CRC64;
MRPAFGHETN SPLLQHFEGE APVSFKSPFP DVEIPNLSVY DFLFGRVDPA DGDRPALIDG
ASGAVTTYRS LVAQINGVAG ALAARGLAVG EVVGLHSPNV PAFASVFHGI LRAGGVATTI
NALYTAEDIA KQLTDSKAKF LFTVSPLLPQ AKDAAAKVGI PVANVIVLDG ADGHPSLTDL
LAERAPAPEV SFDPATQLAV LPYSSGTTGR PKGVMLTHRN LVANVCQINP RMGIGADDTL
LAVLPFFHIY GMTVLLNAAL YNRASLVTMP KFDLVEFLSI VSGQKCTYVF IAPPVAVALA
KHPLVDDYDL SSVHSIFSGA APLDQELGKA VANRLGCRVR QGYGMSEMSP VSHAIPFDRD
DIALDSVGPS IANMECKLVD PATGEEVAYP ADGVSAPGEL WCKGPNIMAG YLGNDEATAE
TLDADGYLHT GDIATVDSEG VVTIVDRMKE LIKYKGYQVP PAELEALLLT HPQIADAAVI
GVLDDEGEEV PKAFVVRQPG AELDEAAVIG FVAERVSPHK KVRKVEFIDL VPKSAAGKIL
RKDLRAAETA GR
//
