ID Q0SCD8_RHOJR Unreviewed; 535 AA.
AC Q0SCD8;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=Probable transcriptional regulator, IclR family protein {ECO:0000313|EMBL:ABG94798.1};
GN OrderedLocusNames=RHA1_ro02995 {ECO:0000313|EMBL:ABG94798.1};
OS Rhodococcus jostii (strain RHA1).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=101510 {ECO:0000313|EMBL:ABG94798.1, ECO:0000313|Proteomes:UP000008710};
RN [1] {ECO:0000313|Proteomes:UP000008710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RHA1 {ECO:0000313|Proteomes:UP000008710};
RX PubMed=17030794; DOI=10.1073/pnas.0607048103;
RA McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C.,
RA Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H.,
RA Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H.,
RA Smailus D., Siddiqui A.S., Marra M.A., Jones S.J.M., Holt R.,
RA Brinkman F.S.L., Miyauchi K., Fukuda M., Davies J.E., Mohn W.W.,
RA Eltis L.D.;
RT "The complete genome of Rhodococcus sp. RHA1 provides insights into a
RT catabolic powerhouse.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006).
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DR EMBL; CP000431; ABG94798.1; -; Genomic_DNA.
DR RefSeq; WP_011595668.1; NC_008268.1.
DR AlphaFoldDB; Q0SCD8; -.
DR KEGG; rha:RHA1_ro02995; -.
DR PATRIC; fig|101510.16.peg.3024; -.
DR eggNOG; COG1414; Bacteria.
DR HOGENOM; CLU_551766_0_0_11; -.
DR OrthoDB; 4068713at2; -.
DR Proteomes; UP000008710; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 2.
DR Pfam; PF01614; IclR; 2.
DR SMART; SM00346; HTH_ICLR; 2.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51077; HTH_ICLR; 2.
DR PROSITE; PS51078; ICLR_ED; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008710};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..64
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 65..253
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
FT DOMAIN 271..332
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 333..516
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 535 AA; 56790 MW; 7A8A9A127301BC4D CRC64;
MNAIQLLTKA GQIVDELARL GPSTPAELAK VVAEPRPSVY RILTALEQIS VVRQAGEGRL
ELGIGLLRWS DAAVEAFVDK GELRRQLRWV REQLGMNVFF CVPHEHGVLS LDQVDGAVVD
MLDLGPGRML PRFAGAAPRA LLAFESPEVQ DSVCAGAPFG RLASGTPTTA QDLRELLDNT
IARGWSVDDS EVVEGVASVA VPVRRDDGGV AGAIAVAGLR ESVLAQQDVA GRVLTVAAEA
LAAAMARAQA TGPRSDATHN GVAQPSETRA PALIVRAGAL MEALARERIA TSTRLTEILD
EPVSSVYRML ATLSEIGWVE QIGHRGAYRV GGRLLSLSGE LTRRLDIRRA AGPVLRAIHE
ATGETTFMCV RHGTRAVCIE RVDGIRVNSR VLRLGRSLPL HVGAAPRALL AFEDRAAWDE
YASAALSEDL LHMGSRSTLY AELDEIRSLG FALSDNTVTP GIAAVGAPIF DHRGDVAASL
SVSGLRDGVL AQPAHGRSVT DLVLWGAAEL SRYLGFDVAR LSEAPRSSAA NALPS
//
