ID Q0SRU7_CLOPS Unreviewed; 727 AA.
AC Q0SRU7;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Stage V sporulation protein D {ECO:0000313|EMBL:ABG86427.1};
GN Name=spoVD_2 {ECO:0000313|EMBL:ABG86427.1};
GN OrderedLocusNames=CPR_1846 {ECO:0000313|EMBL:ABG86427.1};
OS Clostridium perfringens (strain SM101 / Type A).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=289380 {ECO:0000313|EMBL:ABG86427.1, ECO:0000313|Proteomes:UP000001824};
RN [1] {ECO:0000313|EMBL:ABG86427.1, ECO:0000313|Proteomes:UP000001824}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM101 / Type A {ECO:0000313|Proteomes:UP000001824};
RX PubMed=16825665; DOI=10.1101/gr.5238106;
RA Myers G.S., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., Deboy R.T.,
RA Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H.,
RA Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A.,
RA Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D.,
RA Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J.,
RA Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B.,
RA Paulsen I.T.;
RT "Skewed genomic variability in strains of the toxigenic bacterial pathogen,
RT Clostridium perfringens.";
RL Genome Res. 16:1031-1040(2006).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP000312; ABG86427.1; -; Genomic_DNA.
DR AlphaFoldDB; Q0SRU7; -.
DR KEGG; cpr:CPR_1846; -.
DR Proteomes; UP000001824; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR011927; SpoVD_pbp.
DR NCBIfam; TIGR02214; spoVD_pbp; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR PROSITE; PS51178; PASTA; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 603..663
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 668..727
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 213..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 79637 MW; 55C3FC08D52F2F32 CRC64;
MKAKKKNKKI KLNKGRVLAF LLAIAILFLA LSGRLLYISI FRSKDYKAMA EEQWTNEIQI
DARRGRILDR NNRELAVTAN VFRVDLDLIT LRKYIDKKDT DNIEIAKLLA EALEMDEEKV
LSRIELTYPS GNPANSATLI RRIEKEKADK VKELDINGVI VSEDTKRYYP NGDFLSHTLG
TTNADGEGLS GLELYYNEEL MGIPGVRVSE VSGNSTSNPY SETSFTPPVD GKDMTLTIDE
NIQYFVEKVA EDALNKHNAD SVSIAVMNPN NGEILGMVNK PGFNPNNPYE GSEAFKGKDE
SAKLQNMWRN TIVSDAFEPG SIFKIITSIA AIEENIAGKD EVYYCDGSLN VAGKNIKCWK
PGGHGVQNFN QTLENSCNVA FMEMGAKLGA EKLNEYIKLF GFGTQSGIDL PGEATGIVKN
VEDISSVDLA TISFGQTNTM NGIQFMTALN AVANGGDLIQ PHIMKELSHK DDNGTKIIDE
VFVPKIQENI VDEKSTMRVK EALESTVSNG SSKDAGIEGI KVAGKTGTAE KVDSETGTYG
AGYIASFAGF APYDNPQVSL IVIIDNPKNG EHFGGIVAAP FAGELFNNIF NYISLNEGQL
DVKDESVIIT DLRGDKVTSA EKTLNELGIN CVIEGDGTFV TSVKPIPGYK VKKGDSITLY
AGSRFDRNEK EIVVPDFRKL NKEEAEEILK SLGLKGEFEG EGEIKEQSIS AGEIIKSGYK
IKFKLEG
//
