ID Q0U563_PHANO Unreviewed; 880 AA.
AC Q0U563;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=Beta-mannosidase B {ECO:0000256|ARBA:ARBA00041069};
DE EC=3.2.1.25 {ECO:0000256|ARBA:ARBA00012754};
DE AltName: Full=Mannanase B {ECO:0000256|ARBA:ARBA00041614};
GN ORFNames=SNOG_13101 {ECO:0000313|EMBL:EAT79428.1};
OS Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS blotch fungus) (Parastagonospora nodorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC Parastagonospora.
OX NCBI_TaxID=321614 {ECO:0000313|EMBL:EAT79428.1, ECO:0000313|Proteomes:UP000001055};
RN [1] {ECO:0000313|Proteomes:UP000001055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173
RC {ECO:0000313|Proteomes:UP000001055};
RX PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA Hane J.K., Lowe R.G., Solomon P.S., Tan K.C., Schoch C.L., Spatafora J.W.,
RA Crous P.W., Kodira C., Birren B.W., Galagan J.E., Torriani S.F.,
RA McDonald B.A., Oliver R.P.;
RT "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT analysis of the wheat pathogen Stagonospora nodorum.";
RL Plant Cell 19:3347-3368(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-mannose residues
CC in beta-D-mannosides.; EC=3.2.1.25;
CC Evidence={ECO:0000256|ARBA:ARBA00000829};
CC -!- PATHWAY: Glycan metabolism; N-glycan degradation.
CC {ECO:0000256|ARBA:ARBA00004740}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family. Beta-
CC mannosidase B subfamily. {ECO:0000256|ARBA:ARBA00038429}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH445349; EAT79428.1; -; Genomic_DNA.
DR RefSeq; XP_001803316.1; XM_001803264.1.
DR AlphaFoldDB; Q0U563; -.
DR STRING; 321614.Q0U563; -.
DR EnsemblFungi; SNOT_13101; SNOT_13101; SNOG_13101.
DR GeneID; 5980231; -.
DR KEGG; pno:SNOG_13101; -.
DR VEuPathDB; FungiDB:JI435_131010; -.
DR eggNOG; KOG2230; Eukaryota.
DR HOGENOM; CLU_005015_1_1_1; -.
DR InParanoid; Q0U563; -.
DR OMA; QFACASY; -.
DR OrthoDB; 2504097at2759; -.
DR Proteomes; UP000001055; Unassembled WGS sequence.
DR GO; GO:0004567; F:beta-mannosidase activity; IBA:GO_Central.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006516; P:glycoprotein catabolic process; IBA:GO_Central.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041447; Mannosidase_ig.
DR PANTHER; PTHR43730; BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43730:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF17786; Mannosidase_ig; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001055}.
FT DOMAIN 202..312
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 708..808
FT /note="Mannosidase Ig/CBM-like"
FT /evidence="ECO:0000259|Pfam:PF17786"
SQ SEQUENCE 880 AA; 101010 MW; 86945F0A9E6EA1AB CRC64;
MTHPDNFAFT STSLDSNWTF KQGGRDSTDE YLPANDLPTE IYRDLLKNEK ISDPFQDLNE
LSVRWVGDQT WTYRSTFAAP ASYEKPGTVT RLKLEGLDTF ASVYLNDEQI LVSDNMFIEH
YIDVTEKLRL QSNTLEIVFE SARKKGLELV KEHNNHRFIV HQTEISRGPV RKAQYQWGWD
WGPILMSYGP WKPIWLETFV CEIKELSLYY ELSADLKSAH LTASISCLGP VNGVMFTILE
KGTNTEIASK YINSPESEMS VTVSASFELD NIALWWPRGY GSQALYSVRA EARGRGPGAT
NLHGCSHTFG FRKVKLVQEP DSDGTSFYFR INNVDIFTGG SCWIPVDSFL TRISDENYRS
WVQLAAEGNQ NMLRVWGGGI YEADALYEAA DELGIMIWQD FMFACASYPA YPEYLASVEQ
EARQNVRRLR HHPSLVIWAG NNEDYQIVER YGLEYDFKNK DTEAWLQTDF PARYIYEHLL
PNVIQDECPS IPYHPSSPFG NGESMTLNVD PTVGDIHQWN VWNGTAEPYQ RLPDMGGRFV
SEFGIEAYPH VSTLEKCITQ RQERAPGSMT MEFRNKAVGH ERRFMSYVPE NFRMRHDLEG
FTHLTQVMQA DAMSWAYKGW RRQWGTPKNR KCGGVLVWQL NDCWPTISWA VVDYDLVPKP
AYYAIKRAMK PVTISVQRKF RPWTMRPADE LWQRDTGHID MQNLWRNGEF DVWITNGTRE
ELKGEIAVKC FSVRTGETIR TLSKQDMLIA SNGTTEFLKD HVLVAEKVQG ANESFNIATT
DPYVVQVLLC IDGVCVASDT AWPDPIKYLN FDDRQLDVRC HDDDSKVILM AAKPIKGFVF
REKKGMKLSD NGFDLMPHES KEVVVKGCTA HELKWLYIGM
//
